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PIK3CB/PIK3R1 (p110 beta/p85 alpha) Recombinant Human Protein
Catalog number: PV6454
PIK3CB/PIK3R1 (p110 beta/p85 alpha) Recombinant Human Protein
Catalog number: PV6454
Product Overview
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PIK3CB/PIK3R1 (p110β/p85α) is a phosphoinositide-3-kinase (PI3K) comprised of a catalytic subunit, p110β, and a regulatory subunit, p85α, encoded by the PIK3CB and PIK3R1 genes respectively. As with other members of the PI3K family, p110β has important regulatory roles in cellular processes including cell survival, proliferation, and differentiation. It affects growth factor signaling and survival by phosphorylating inositol lipids. PTEN-deficient cancer cells have been observed to depend on p110β signaling.
PIK3CB/PIK3R1 (p110β/p85α) Recombinant Human Protein is:
• Available in 3 convenient sizes
• Validated in our Adapta™ and Kinase Binding assays
• A full-length protein that can help advance your research when used in validated assays
Related assay platforms:
LanthaScreen™ Kinase Binding Assay
Adapta™ Kinase Activity Assay
PIK3CB/PIK3R1 (p110β/p85α) Recombinant Human Protein is:
• Available in 3 convenient sizes
• Validated in our Adapta™ and Kinase Binding assays
• A full-length protein that can help advance your research when used in validated assays
Related assay platforms:
LanthaScreen™ Kinase Binding Assay
Adapta™ Kinase Activity Assay
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_006210.1, NP_852664.1
Gene ID (Entrez)
PIK3R1, PIK3CB
Molecular Weight
123.7 kDa, 84.7 kDa
Quantity
20 µg
Gene Alias
phosphatidylinositol-4, 5-bisphosphate 3-kinase, p110 beta/p85 alpha, p110β/p85α
KinaseFamily
PI3 Kinase
Recombinant
Yes
Protein Tag
His Tag
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Full Length, Recombinant, Active
Form
Liquid
Validated Application
Kinase Assay
Species
Human
Research Category
Signal Transduction, Drug Development, Oncology
Contents & Storage
Storage buffer: 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol.
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.