Thermo Scientific™

Lab Vision™ CD3ε (Early T-Cell Marker) Ab-1, Rabbit Polyclonal Antibody

 Related applications:
Anatomical Pathology

Obtain accurate and reproducible results in immunohistochemistry applications with Thermo Scientific™ CD3ε (Early T-Cell Marker) Ab-1, Rabbit Polyclonal Antibody, one marker in a comprehensive antibody portfolio that addresses all major disease states, ensuring the ideal tests are always available.

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Description

CD3 consists of five different polypeptide chains (designated as γ, δ, ε, ζ, and η). The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). It is involved in signal transduction to the T cell interior following antigen recognition. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Does not react with rat. Others not known.

Epitope: aa 156-168 of ε-chain

Immunogen: A synthetic 13-mer peptide, corresponding to aa 156-168 of the ε-chain of human CD3 protein

Molecular Weight: ∽20kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

General References:

1. Mason DY et al. Journal of Clinical Pathology, 1989, 42(11):1194-200.

2. Cibull ML et al. Histopathology, 1989, 15(6):599-605.

3. Mason DY et al. Journal of Clinical Pathology, 1988, 41(2):121-7.



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