PDGFRα, Rabbit Polyclonal Antibody

Thermo Scientific™  Related applications: Anatomical Pathology

Employ one marker in a comprehensive antibody portfolio that addresses all major disease states with the Thermo Scientific™ PDGFRα, Rabbit Polyclonal Antibody.

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Description

PDGFR (Platelet Derived Growth Factor Receptor) exhibits two different isoforms, alpha; and beta; coded by two different genes. PDGF A receptors are expressed in oligodendrocyte progenitor cells and PDGF B receptors are expressed on neurons. This antibody is specific for PDGFR, alpha; and does not react with PDGFR, beta;.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Others not tested.

Epitope: C-terminus

Immunogen: A synthetic peptide derived from C-terminal of human PDGFRα

Molecular Weight: 190kDa

Positive Control: Skin and ovarian CA

Cellular Localization: Cytoplasmic and cell membrane This antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)


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