Thermo Scientific™

Lab Vision™ GLUT-1, Rabbit Polyclonal Antibody

Related applications:

Anatomical Pathology

Obtain accurate, reproducible results in immunohistochemistry, western blotting and immunofluorescence experiments with Thermo Scientific™ GLUT-1, Rabbit Polyclonal Antibody, one marker in a comprehensive antibody portfolio that addresses all major disease states, ensuring the ideal tests are always available.

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Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF-1 induced signaling. GLUT-1 is detectable in many human tissues including those of the colon, lung, stomach, esophagus, and breast. GLUT-1 immunoreactivity in some cancers, including trans carcinoma of the urinary bladder, has been associated with aggressive behavior.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Rat. Others not tested.

Epitope: C-terminal

Immunogen: A synthetic peptide derived from C-terminal of human GLUT-1

Molecular Weight: 55 kDa, 45 kDa depending on the extent of glycosylation

Positive Control: Rat brain lysate; Breast CA, squamous cell CA, nonsmall-cell lung CA and esophageal CA

Cellular Localization: Membrane and focal cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence