Thermo Scientific™

Lab Vision™ CD105/Endoglin/TGF β 1/3 Receptor, Rabbit Polyclonal Antibody

 Related applications:
Anatomical Pathology

Obtain accurate and reliable results in immunohistochemistry experiments with Thermo Scientific™ CD105/Endoglin/TGF β 1/3 Receptor, Rabbit Polyclonal Antibody, one marker in a comprehensive antibody portfolio that addresses all major disease states, ensuring the ideal tests are always available.

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Description

CD105 or Endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Up-regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation-associated endothelial cell marker. CD105 binds to TGF-β1 and β3 with high affinity but not TGF-β2.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Others not tested

Epitope: Not known

Immunogen: Recombinant protein encoding aa 26-176 of human CD105

Molecular Weight: 95 kDa (monomer) and 190 kDa (dimer)

Positive Control: Tonsil, Placenta

Cellular Localization: Membrane and cytoplasm

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)


Documents

Manuals & protocols