CD138, Rabbit Polyclonal Antibody

Thermo Scientific™  Related applications: Anatomical Pathology

Ensure accurate, reproducible results in immunohistochemistry procedures with Thermo Scientific™ CD138, Rabbit Polyclonal Antibody.

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Description

CD138/Syndecan-1 is a transmembrane heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycan. CD138 is expected to play a role in cell adhesion. It is expressed on the surface of pre-B cells and plasma cells but is absent from mature B cells. It is a selective marker for B cell lymphoblastic leukemia and lymphoplasmocytoid leukemia. It is lost from the apoptotic myeloma cells; hence is a useful marker for viable myeloma cells.

Host Species: Rabbit

Species Reactivity: Human. Others not tested

Epitope: aa 18-218

Immunogen: Recombinant protein encoding aa 18-218 human CD138

Molecular Weight: 30.5kDa (core protein); 85-92kDa (depending upon glycosaminoglycans)

Positive Control: Tonsil

Cellular Localization: Plasma cell and Membrane

Recommended for:

  • Immunohistochemistry

Note:

USA: RUO; Int'l: RUO



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