Placental Alk. Phosphatase (PLAP), Rabbit Monoclonal Antibody

Thermo Scientific™  Related applications: Anatomical Pathology

Employ part of a comprehensive antibody portfolio with the Thermo Scientific™ Placental Alk. Phosphatase (PLAP), Rabbit Monoclonal Antibody. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

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Description

Reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. This antibody is highly specific to PLAP and shows no cross-reaction with other isoenzymes of alkaline phosphatases. It is useful in the identification of testicular germ cell tumors. Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA).

Host Species: Rabbit

Clone: SP15

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant protein encoding human Placental Alkaline Phosphatase (PLAP)

Molecular Weight: 60-70kDa

Positive Control: Placenta or seminoma

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)


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