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Invitrogen
Human MRPS5 (aa 356-426) Control Fragment Recombinant Protein
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Product Details
RP-101798
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
QETHQQLADKKGLHVVEIREECGPLPIVVASPRGPLRKDPEPEDEVPDVKLDWEDVKTAQGMKRSVWSNLK
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63173. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-S5 (mitochondrial ribosomal protein S5), alternatively known as S5mt, is a 430 amino acid mitochondrial protein belonging to the ribosomal protein S5P family. A component of the 28S subunit, MRP-S5 contains one S5 DRBM domain and exists as two alternatively spliced isoforms. The gene encoding MRP-S5 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstrom syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 28S ribosomal protein S5, mitochondrial; mitochondrial 28S ribosomal protein S5; MRP-S5; Small ribosomal subunit protein uS5m
Gene Aliases: MRP-S5; MRPS5; S5mt
UniProt ID: (Human) P82675
Entrez Gene ID: (Human) 64969
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