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Invitrogen
Human RGS9 (aa 388-522) Control Fragment Recombinant Protein
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Product Details
RP-105727
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
LDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTIC
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82497. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The cascade of biochemical reactions within the vision system is complex and contains numerous steps taking place in nanoseconds. RGS is a family of GTPase accelerating proteins (GAPs). RGS9 is a member of this family and is the predominant source of GAP activity in rod outer segments. RGS9-1, found predominately in vertebrate cone and rod photoreceptors, is a useful model for understanding how rapid recovery kinetics of the light responses in retinal photoreceptors take place.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC111763; MGC26458; Regulator of G-protein signaling 9; regulator of G-protein signalling 9; RGS9
Gene Aliases: PERRS; RGS9; RGS9L
UniProt ID: (Human) O75916
Entrez Gene ID: (Human) 8787
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