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Highest antigen sequence indentity to the following orthologs: Mouse (80%), Rat (80%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82319. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
MMEL1 is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. MMEL1 is a type II transmembrane protein and is thought to be expressed as a secreted protein. The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 3.4.24; EC 3.4.24.11; Membrane metallo-endopeptidase-like 1; Membrane metallo-endopeptidase-like 2; MGC119454; MGC119455; MGC119456; NEP2; NEP2(m); NEPII; NEPIIMGC119456; Neprilysin II; Neprilysin-2; NL2NL1; soluble secreted endopeptidase; zinc metallopeptidase
Gene Aliases: MELL1; MMEL1; MMEL2; NEP2; NEPII; NL1; NL2; SEP
UniProt ID: (Human) Q495T6
Entrez Gene ID: (Human) 79258
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