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Highest antigen sequence indentity to the following orthologs: Mouse (63%), Rat (63%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82281. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
PTP PEST is an 88 kDa cytosolic protein tyrosine phosphatase which is ubiquitiously expressed in mammalian tissues. PTP PEST exhibits a high specific activity when assayed in vitro with artificial tyrosine-phosphorylated substrates. PTP PEST is subject to regulation via phosphorylation of ser 39 and is catalyzed by both protein kinase C and protein kinase A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: pest; Protein-tyrosine phosphatase G1; PTP-PEST; PTPG1; tcag7.1075; tumor suppressor; tumor suppressor; pTP; Tyrosine-protein phosphatase non-receptor type 12; unnamed protein product
Gene Aliases: PTP-PEST; PTPG1; PTPN12
UniProt ID: (Human) Q05209
Entrez Gene ID: (Human) 5782
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