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Invitrogen
Human PLEKHF2 (aa 63-143) Control Fragment Recombinant Protein
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Product Details
RP-93912
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
VYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSGKTPSN
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55199. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
PLEKHF2 may play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EAPF; Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains; PH and FYVE domain-containing protein 2; PH domain-containing family F member 2; Phafin-2; Phafin2; pleckstrin homology domain containing, family F (with FYVE domain) member 2; Pleckstrin homology domain-containing family F member 2; Zinc finger FYVE domain-containing protein 18
Gene Aliases: EAPF; PHAFIN2; PLEKHF2; ZFYVE18
UniProt ID: (Human) Q9H8W4
Entrez Gene ID: (Human) 79666
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