Thermo Scientific™

Epithelial Specific ETS3 (ESE3), Rat Monoclonal Antibody

 Related applications:
Anatomical Pathology

Ensure accurate, reproducible results in western blotting experiments with Thermo Scientific™ Epithelial Specific ETS3 (ESE3), Rat Monoclonal Antibody.

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Description

ESE3 (Epithelial Specific ETS) belongs to a subgroup of related polypeptides within the ETS family of transcription factors. The members of the ESE group are expressed primarily in epithelial cells, and share a common structure with other subgroups within the family. ESE-3 is expressed in epithelial cells originating in a variety of tissues including trachea, salivary gland, esophagus, colon, prostate, seminal vesicle, breast, bladder, and uterus, among others. The expression of ESE-3 in trachea and colon appears to segregate mainly with epithelial cells of a secretory phenotype. In all cases, ESE3 expression appears to be restricted to differentiated epithelial cells. ESE-3 expression is consistently lost in carcinomas of various epithelial origins, including but not limited to, bladder, squamous carcinomas of stratified epithelia, breast ductal carcinoma, and cervical carcinoma.

Host Species: Rat

Clone: 5A5.5

Species Reactivity: Human. Does not cross-react with mouse. Others not tested.

Immunogen: Purified His-tagged recombinant ESE-3 expressed in E. coli

Molecular Weight: 36 kDa

Positive Control: LnCAP

Cellular Localization: Nuclear staining

Recommended for:

  • Western Blotting

Note:

USA: RUO; Int'l: RUO

General References:

1. Tugores, A., et al. (2001) J. Biol. Chem., 276(23): 20397-20406



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