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OriGene
REN Monoclonal Antibody (OTI1D3), TrueMAB™
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Product Details
TA807103
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI1D3
Immunogen
Human recombinant protein fragment corresponding to amino acids 131-406 of human REN produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: angiotensin-forming enzyme; Angiotensinogenase; aspartyl-protease; EC 3.4.23; EC 3.4.23.15; FLJ10761; REN; Renin; renin precursor, renal; unnamed protein product
Gene Aliases: ADTKD4; HNFJ2; REN; RTD
UniProt ID: (Human) P00797
Entrez Gene ID: (Human) 5972
kidney development
mesonephros development
angiotensin maturation
regulation of blood volume by renin-angiotensin
renin-angiotensin regulation of aldosterone production
regulation of blood vessel size by renin-angiotensin
proteolysis
regulation of blood pressure
male gonad development
response to xenobiotic stimulus
hormone-mediated signaling pathway
gene expression
response to lipopolysaccharide
response to immobilization stress
angiotensin-activated signaling pathway
drinking behavior
regulation of MAPK cascade
cell maturation
beta-amyloid metabolic process
response to cAMP
response to cGMP
cellular response to xenobiotic stimulus
juxtaglomerular apparatus development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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