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OriGene
VAX1 Monoclonal Antibody (OTI4E5), TrueMAB™
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FIGURE: 1 / 3
VAX1 Antibody (TA811439) in IHC (P)
Immunohistochemical staining of paraffin-embedded human endometrium tissue within the normal limits using anti-VAX1 mouse monoclonal antibody. This figure shows negative staining. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA811439)(1:150).
Product Details
TA811439
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4E5
Immunogen
Full length human recombinant protein of human VAX1 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. Genes of this family are involved in the regulation of body development and morphogenesis. The most conserved genes, called HOX genes are found in special gene clusters. This gene belongs to the VAX subfamily and lies in the vicinity of the EMX homeobox gene family. Another member of VAX family is located on chromosome 2. The encoded protein may play an important role in the development of anterior ventral forebrain and visual system. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: unnamed protein product; Ventral anterior homeobox 1
Gene Aliases: MCOPS11; VAX1
UniProt ID: (Human) Q5SQQ9
Entrez Gene ID: (Human) 11023
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
chromatin DNA binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
neuron migration
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nervous system development
neuroblast proliferation
negative regulation of neuroblast proliferation
axon guidance
central nervous system development
brain development
glial cell differentiation
neuron differentiation
skeletal muscle cell differentiation
camera-type eye development
astrocyte differentiation
palate development
neuroepithelial cell differentiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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