Prepare oximes of steroids and ketoacids prior to silylation with the Thermo Scientific™ Methoxamine (MOX) Reagent. It prevents the formation of multiple derivatives when enols are present during silylation, thereby ensuring optimal quantitation. The reagent is a 2% solution of methoxyamine–hydrogen chloride in pyridine.
Prevents formation of multiple derivatives when enols are present during silylation
Supplied in amber Thermo Scientific Hypo-Vial Sample Storage Vial with septum and crimp top
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1. Chiabrando, C., et al. (1987). Anal. Biochem. 163, 255-262.
2. Horning, M.G., et al. (1968). Anal. Biochem. 22, 284.