Thermo Scientific™

Vanquish™ Online 2D-LC Systems

Catalog number: VQ-ONLINESPE
Thermo Scientific™

Vanquish™ Online 2D-LC Systems

Catalog number: VQ-ONLINESPE

Improve the analysis of complex samples or simplify the separation of difficult-to-resolve analytes with Thermo Scientific™ Vanquish™ Online 2D-LC Systems. Select from one of four configurations focused on online SPE or various heart-cutting two-dimensional liquid chromatography (LC-LC) workflows. The modular instrument can use modules from the Vanquish Core HPLC, Vanquish Flex UHPLC or Vanquish Horizon UHPLC systems, retaining the performance, robustness, and ease of use of the Vanquish platform, while offering maximum application flexibility.


View Vanquish Online 2D-LC resources

 
Catalog Number
VQ-ONLINESPE
Unit Size
Each
Description
Vanquish Online SPE HPLC and UHPLC System
Price (USD)
Full specifications
DescriptionVanquish Online SPE HPLC and UHPLC System
For Use With (Application)Clean up and pre-concentrate the sample prior to mass spectrometry (MS) detection to reduce the matrix effect that can suppress or enhance signal, affecting data quality.
For Use With (Equipment)Vanquish Horizon, Vanquish Flex or Vanquish Core Modules
TypeIntegrated (U)HPLC system for automated sample clean-up and pre-concentration
Max. Pressure1500 bar (22,000 psi) depending on configuration
Unit SizeEach
Catalog Number
Unit Size
Each
Description
Vanquish Loop Heart-Cut 2D-LC System
Price (USD)
Full specifications
DescriptionVanquish Loop Heart-Cut 2D-LC System
For Use With (Application)Reveal hidden impurities underneath the analyte of interest by applying complementary chromatographic mechanisms, such as combining ion-exchange and size exclusion chromatography for exploration of large molecules, to gain more separation power.
For Use With (Equipment)Vanquish Horizon, Vanquish Flex or Vanquish Core Modules
TypeIntegrated (U)HPLC system for peak purity confirmation by LC-LC
Max. Pressure1500 bar (22,000 psi) depending on configuration
Unit SizeEach
Catalog Number
Unit Size
Each
Description
Vanquish Trap Heart-Cut 2D-LC System
Price (USD)
Full specifications
DescriptionVanquish Trap Heart-Cut 2D-LC System
For Use With (Application)Resolve solvent incompatibility between UV and MS-methods and peak dilution during chromatrographic steps by trapping with optional online solvent modulation to explore even low analyte concentrations like tryptic digests.
For Use With (Equipment)Either Vanquish Horizon or Vanquish Flex Modules
TypeIntegrated (U)HPLC system for peak purity confirmation by LC-LC and enable UV/MS method compatibility
Max. Pressure1500 bar (22,000 psi) depending on configuration
Unit SizeEach
Catalog Number
Unit Size
Each
Description
Vanquish Simple Switch 2D-LC System
Price (USD)
Full specifications
DescriptionVanquish Simple Switch 2D-LC System
For Use With (Application)Apply 2D-LC for difficult samples and separations that need more separation power, or use two independent 1D flowpaths (dual LC) to focus on method development acceleration or high sample throughput.
For Use With (Equipment)Either Vanquish Horizon or Vanquish Flex Modules
TypeSwitch between a 2D-LC instrument and a Dual LC instrument
Max. Pressure1500 bar (22,000 psi) depending on configuration
Unit SizeEach
Showing 4 of 4
Catalog NumberSpecificationsUnit SizeDescriptionPrice (USD)
VQ-ONLINESPEFull specifications
EachVanquish Online SPE HPLC and UHPLC SystemRequest A Quote
DescriptionVanquish Online SPE HPLC and UHPLC System
For Use With (Application)Clean up and pre-concentrate the sample prior to mass spectrometry (MS) detection to reduce the matrix effect that can suppress or enhance signal, affecting data quality.
For Use With (Equipment)Vanquish Horizon, Vanquish Flex or Vanquish Core Modules
TypeIntegrated (U)HPLC system for automated sample clean-up and pre-concentration
Max. Pressure1500 bar (22,000 psi) depending on configuration
Unit SizeEach
VQ2D-HCUT-LOOPFull specifications
EachVanquish Loop Heart-Cut 2D-LC SystemRequest A Quote
DescriptionVanquish Loop Heart-Cut 2D-LC System
For Use With (Application)Reveal hidden impurities underneath the analyte of interest by applying complementary chromatographic mechanisms, such as combining ion-exchange and size exclusion chromatography for exploration of large molecules, to gain more separation power.
For Use With (Equipment)Vanquish Horizon, Vanquish Flex or Vanquish Core Modules
TypeIntegrated (U)HPLC system for peak purity confirmation by LC-LC
Max. Pressure1500 bar (22,000 psi) depending on configuration
Unit SizeEach
VQ2D-HCUT-TRAPFull specifications
EachVanquish Trap Heart-Cut 2D-LC SystemRequest A Quote
DescriptionVanquish Trap Heart-Cut 2D-LC System
For Use With (Application)Resolve solvent incompatibility between UV and MS-methods and peak dilution during chromatrographic steps by trapping with optional online solvent modulation to explore even low analyte concentrations like tryptic digests.
For Use With (Equipment)Either Vanquish Horizon or Vanquish Flex Modules
TypeIntegrated (U)HPLC system for peak purity confirmation by LC-LC and enable UV/MS method compatibility
Max. Pressure1500 bar (22,000 psi) depending on configuration
Unit SizeEach
VQ2D-2SFull specifications
EachVanquish Simple Switch 2D-LC SystemRequest A Quote
DescriptionVanquish Simple Switch 2D-LC System
For Use With (Application)Apply 2D-LC for difficult samples and separations that need more separation power, or use two independent 1D flowpaths (dual LC) to focus on method development acceleration or high sample throughput.
For Use With (Equipment)Either Vanquish Horizon or Vanquish Flex Modules
TypeSwitch between a 2D-LC instrument and a Dual LC instrument
Max. Pressure1500 bar (22,000 psi) depending on configuration
Unit SizeEach
Showing 4 of 4

Add separation power, gain more information

  • Flexible configurations with the modular instrument design to tailor a system for your application needs
  • Confidence to confirm peak verification, purity and identity of complex samples by LC-LC
  • Smooth adoption of two-dimensional liquid chromatography workflow utilizing downloadable software templates

Vanquish™ Online SPE HPLC and UHPLC Systems
Ensure analyte pre-concentration and sample clean-up in an automated repeatable workflow while saving solvent and time.

Vanquish™ Loop Heart-Cut 2D-LC Systems
Collect one or multiple fractions of the first-dimension separation in a sample loop and transfer the cut-out fraction(s) in an automated workflow to an orthogonal column chemistry for confidence in peak purity.

Vanquish™ Trap Heart-Cut 2D-LC Systems
Transfer single fractions from the first-dimension column to a trap column before transferring to the second dimension column, allowing you to achieve mobile phase compatibility between dimensions to support multiple combinations of 1D and 2D methods for simplified multi-dimensional liquid chromatography method development.

Vanquish™ Simple Switch™ 2D-LC Systems
For labs looking to do it all in one system, this innovative configuration utilizes the unique Thermo Scientific™ Vanquish™ Dual Split Sampler to efficiently utilize the instrumentation and enable users to seamlessly switch between a Vanquish trap-based heart-cut 2D-LC system and a Thermo Scientific™ Vanquish™ Duo for Dual LC system for confidence and improved productivity within one system.