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Search Thermo Fisher Scientific
Improve the analysis of complex samples or simplify the separation of difficult-to-resolve analytes with Thermo Scientific™ Vanquish™ Online 2D-LC Systems. Select from one of four configurations focused on online SPE or various heart-cutting two-dimensional liquid chromatography (LC-LC) workflows. The modular instrument can use modules from the Vanquish Core HPLC, Vanquish Flex UHPLC or Vanquish Horizon UHPLC systems, retaining the performance, robustness, and ease of use of the Vanquish platform, while offering maximum application flexibility.
Type | Integrated (U)HPLC system for peak purity confirmation by LC-LC and enable UV/MS method compatibility |
Max. Pressure | 1500 bar (22,000 psi) depending on configuration |
Description | Vanquish Trap Heart-Cut 2D-LC System |
For Use With (Application) | Resolve solvent incompatibility between UV and MS-methods and peak dilution during chromatrographic steps by trapping with optional online solvent modulation to explore even low analyte concentrations like tryptic digests. |
For Use With (Equipment) | Either Vanquish Horizon or Vanquish Flex Modules |
Unit Size | Each |
Type | Integrated (U)HPLC system for automated sample clean-up and pre-concentration |
Max. Pressure | 1500 bar (22,000 psi) depending on configuration |
Description | Vanquish Online SPE HPLC and UHPLC System |
For Use With (Application) | Clean up and pre-concentrate the sample prior to mass spectrometry (MS) detection to reduce the matrix effect that can suppress or enhance signal, affecting data quality. |
For Use With (Equipment) | Vanquish Horizon, Vanquish Flex or Vanquish Core Modules |
Unit Size | Each |
Type | Integrated (U)HPLC system for peak purity confirmation by LC-LC |
Max. Pressure | 1500 bar (22,000 psi) depending on configuration |
Description | Vanquish Loop Heart-Cut 2D-LC System |
For Use With (Application) | Reveal hidden impurities underneath the analyte of interest by applying complementary chromatographic mechanisms, such as combining ion-exchange and size exclusion chromatography for exploration of large molecules, to gain more separation power. |
For Use With (Equipment) | Vanquish Horizon, Vanquish Flex or Vanquish Core Modules |
Unit Size | Each |
Type | Switch between a 2D-LC instrument and a Dual LC instrument |
Max. Pressure | 1500 bar (22,000 psi) depending on configuration |
Description | Vanquish Simple Switch 2D-LC System |
For Use With (Application) | Apply 2D-LC for difficult samples and separations that need more separation power, or use two independent 1D flowpaths (dual LC) to focus on method development acceleration or high sample throughput. |
For Use With (Equipment) | Either Vanquish Horizon or Vanquish Flex Modules |
Unit Size | Each |
Catalog Number | Specifications | Unit Size | Description | Price (USD) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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VQ2D-HCUT-TRAP | Each | Vanquish Trap Heart-Cut 2D-LC System | Request A Quote | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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VQ-ONLINESPE | Each | Vanquish Online SPE HPLC and UHPLC System | Request A Quote | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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VQ2D-HCUT-LOOP | Each | Vanquish Loop Heart-Cut 2D-LC System | Request A Quote | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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VQ2D-2S | Each | Vanquish Simple Switch 2D-LC System | Request A Quote | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Add separation power, gain more information
Vanquish™ Online SPE HPLC and UHPLC Systems
Ensure analyte pre-concentration and sample clean-up in an automated repeatable workflow while saving solvent and time.
Vanquish™ Loop Heart-Cut 2D-LC Systems
Collect one or multiple fractions of the first-dimension separation in a sample loop and transfer the cut-out fraction(s) in an automated workflow to an orthogonal column chemistry for confidence in peak purity.
Vanquish™ Trap Heart-Cut 2D-LC Systems
Transfer single fractions from the first-dimension column to a trap column before transferring to the second dimension column, allowing you to achieve mobile phase compatibility between dimensions to support multiple combinations of 1D and 2D methods for simplified multi-dimensional liquid chromatography method development.
Vanquish™ Simple Switch™ 2D-LC Systems
For labs looking to do it all in one system, this innovative configuration utilizes the unique Thermo Scientific™ Vanquish™ Dual Split Sampler to efficiently utilize the instrumentation and enable users to seamlessly switch between a Vanquish trap-based heart-cut 2D-LC system and a Thermo Scientific™ Vanquish™ Duo for Dual LC system for confidence and improved productivity within one system.