Deoxycholic acid, 98.5%

Deoxycholic acid, CAS # 83-44-3, is a bile acid and blood serum metabolite. | CAS: 83-44-3 | C24H40O4 | 392.58 g/mol

Catalog Number	Quantity	Packaging
148145000	500 g	Glass bottle

Catalog number 148145000

Price (USD)

Quantity:

500 g

Packaging:

Glass bottle

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Chemical Identifiers

CAS83-44-3

IUPAC Name(4R)-4-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid

Molecular FormulaC24H40O4

InChI KeyKXGVEGMKQFWNSR-LLQZFEROSA-N

SMILES[H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C

Specifications

Loss on drying=<1 % (140°C, 4 hrs) (under vacuum < 5 mmHg)

Residue after ignition=<0.2 %

Appearance (Form)Crystalline powder

Infrared spectrumConforms

Melting point172°C to 178°C

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Deoxycholic acid is a 5beta-cholan-24-oic acid derivative with hydroxy substitutions at carbons 3 and 12

• Deoxycholic acid’s role is to absorb fats by emulsifying and solubilizing them

Applications

• Deoxycholic acid may be used for laboratory study of submental fat

• Deoxycholic acid is capable of disrupting cell membranes

• In laboratory research applications, deoxycholic acid can be used to solubilize proteins or as a secondary standard

RUO – Research Use Only

General References:

Funabashi, M.; Grove, T.L., Wang, M.; Varma, Y.; McFadden, M.E.; Brown, L.C.; Guo, C.; Higginbottom, S.; Almo, S.C.; Fischbach, M.A. A metabolic pathway for bile acid dehydroxylation by the gut microbiome. Nature. 2020, 582(7813), 566-570.
Peach, M.; Marsh, N.; Macphee, D.J. Protein solubilization: attend to the choice of lysis buffer. Methods Mol Biol. 2012, 869, 37-47.