1,10-Phenanthroline monohydrate, 99+%, Thermo Scientific Chemicals
1,10-Phenanthroline monohydrate, 99+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

1,10-Phenanthroline monohydrate, 99+%, Thermo Scientific Chemicals

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10 g
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250 g
Catalog number A14140.09
also known as A14140-09
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10 g
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Chemical Identifiers
CAS5144-89-8
IUPAC Name1,10-phenanthroline hydrate
Molecular FormulaC12H10N2O
InChI KeyPPQJCISYYXZCAE-UHFFFAOYSA-N
SMILESO.C1=CN=C2C(C=CC3=CC=CN=C23)=C1
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SpecificationsSpecification SheetSpecification Sheet
Assay from Suppliers CofA≥99.0%
Appearance (Color)White to cream
Melting Point (clear melt)95-103°C
FormCrystalline powder or needles
1,10-Phenanthroline monohydrate is useful to study the DNA-protein interactions due to its nuclease activity. It is used as a redox indicator and reagent for spectrophotometric assay of silver. It acts as a chelating ligand for the determination of Fe, Pd and V. It also acts as a matrix metalloproteinase inhibitor. It is a photometric reagent for iron, which forms a red chelate with ferrous (iron II) ion.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1,10-Phenanthroline monohydrate is useful to study the DNA-protein interactions due to its nuclease activity. It is used as a redox indicator and reagent for spectrophotometric assay of silver. It acts as a chelating ligand for the determination of Fe, Pd and V. It also acts as a matrix metalloproteinase inhibitor. It is a photometric reagent for iron, which forms a red chelate with ferrous (iron II) ion.

Solubility
Soluble in ethanol, acetone and methanol. Slightly soluble in water and benzene.

Notes
Working solutions of 1,10-Phenanthroline monohydrate may stable for a few days at refrigerated temperatures. Incompatible with strong oxidizing agents and strong acids.
RUO – Research Use Only

General References:

  1. Redox indicator.
  2. Chelating ligand for the determination of Fe, Pd and V.
  3. Said, N.; Muhammad, R. S.; Qamar, A.; Zahid, H. One Pot Synthesis of 1,10-Phenanthroline-based Shape-Persistent Flouroscent Macrocycle Using Sonogashira Coupling. Lett. Org. Chem. 2015, 12 (7), 504-510.