1,10-Phenanthroline monohydrate is useful to study the DNA-protein interactions due to its nuclease activity. It is used as a redox indicator and reagent for spectrophotometric assay of silver. It acts as a chelating ligand for the determination of Fe, Pd and V. It also acts as a matrix metalloproteinase inhibitor. It is a photometric reagent for iron, which forms a red chelate with ferrous (iron II) ion.
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Applications
1,10-Phenanthroline monohydrate is useful to study the DNA-protein interactions due to its nuclease activity. It is used as a redox indicator and reagent for spectrophotometric assay of silver. It acts as a chelating ligand for the determination of Fe, Pd and V. It also acts as a matrix metalloproteinase inhibitor. It is a photometric reagent for iron, which forms a red chelate with ferrous (iron II) ion.
Solubility
Soluble in ethanol, acetone and methanol. Slightly soluble in water and benzene.
Notes
Working solutions of 1,10-Phenanthroline monohydrate may stable for a few days at refrigerated temperatures. Incompatible with strong oxidizing agents and strong acids.
RUO – Research Use Only
General References:
- Redox indicator.
- Chelating ligand for the determination of Fe, Pd and V.
- Said, N.; Muhammad, R. S.; Qamar, A.; Zahid, H. One Pot Synthesis of 1,10-Phenanthroline-based Shape-Persistent Flouroscent Macrocycle Using Sonogashira Coupling. Lett. Org. Chem. 2015, 12 (7), 504-510.