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Citations & References (32)
Invitrogen™
CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoate (CholEsteryl BODIPY™ FL C12)
Cholesteryl esters consist of a fatty acid esterified to the 3β-hydroxyl group of cholesterol. These very nonpolar species are theRead more
| Catalog Number | Quantity |
|---|---|
| C3927MP | 1 mg |
Catalog number C3927MP
Price (USD)
451,98
Each
Quantity:
1 mg
Price (USD)
451,98
Each
Cholesteryl esters consist of a fatty acid esterified to the 3β-hydroxyl group of cholesterol. These very nonpolar species are the predominant lipid components of atherosclerosis plaque and low- and high-density lipoporotein (LDL and HDL) cores. The green fluorescent BODIPY™ FL C12 cholesteryl ester can be used as a tracer of cholesterol transport and receptor-mediated endocytosis of lipoproteins by fluorescence microscopy and as a general nonexchangeable membrane marker.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical Name or MaterialCholesterol Analogs
Recommended StorageStore in freezer (-5 to -30°C) and protect from light.
Physical FormSolid
Product LineBODIPY
Quantity1 mg
Unit SizeEach
Frequently asked questions (FAQs)
How should I store CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoate (CholEsteryl BODIPY FL C12) (Cat. No. C3927MP) once reconstituted?
What is the molecular weight of CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoate (CholEsteryl BODIPY FL C12) (Cat. No. C3927MP)? Is the molecular weight based on the cholesteryl moiety together with BODIPY?
How do I reconstitute CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoate (CholEsteryl BODIPY FL C12) (Cat. No. C3927MP)?
Citations & References (32)
Citations & References
Abstract
Streptococcal serum opacity factor increases the rate of hepatocyte uptake of human plasma high-density lipoprotein cholesterol.
Journal:Biochemistry
PubMed ID:20879789
Serum opacity factor (SOF), a virulence determinant of Streptococcus pyogenes, converts plasma high-density lipoproteins (HDL) to three distinct species: lipid-free apolipoprotein (apo) A-I, neo HDL, a small discoidal HDL-like particle, and a large cholesteryl ester-rich microemulsion (CERM) that contains the cholesterol esters (CE) of up to ~400000 HDL particles and
Human granulosa cells use high density lipoprotein cholesterol for steroidogenesis.
Journal:J Clin Endocrinol Metab
PubMed ID:9506760
This study examines the ability of human high density lipoproteins (HDL3) to deliver cholesteryl esters to human granulosa cells and describes the selective cholesterol pathway by which this occurs. Luteinized cells obtained from subjects undergoing in vitro fertilization-embryo transfer procedures were incubated with native HDL3 (or radiolabeled or fluorescently labeled
High density lipoprotein (HDL) particle uptake mediated by scavenger receptor class B type 1 results in selective sorting of HDL cholesterol from protein and polarized cholesterol secretion.
Journal:J Biol Chem
PubMed ID:11301333
'High density lipoprotein (HDL) mediates reverse transport of cholesterol from atheroma foam cells to the liver, but the mechanisms of hepatic uptake and trafficking of HDL particles are poorly understood. In contrast to its accepted role as a cell surface receptor, scavenger receptor class B type 1 (SR-BI) is shown
Intracellular localization and metabolism of chylomicron remnants in the livers of low density lipoprotein receptor-deficient mice and apoE-deficient mice. Evidence for slow metabolism via an alternative apoE-dependent pathway.
Journal:J Biol Chem
PubMed ID:7499399
'The metabolism of chylomicron remnants in mice deficient in low density lipoprotein receptor (LDLr) or apolipoprotein E (apoE) was compared with that of control C57BL/6J mice. Mice were injected intravenously with chylomicron-like emulsions labeled with radioactive lipids. Blood samples were taken at fixed time intervals from the retro-orbital sinus, and
Direct visualization of lipid deposition and reverse lipid transport in a perfused artery : roles of VLDL and HDL.
Journal:Circ Res
PubMed ID:10764410
'The major goal of this study was to determine the interactions of VLDL surface and core lipids with the artery wall. We first demonstrated in vitro that surface lipid in VLDL could be traced using the phospholipid-like fluorescent probe 1,1''-dioctadecyl-3,3, 3'',3''-tetramethyl-indocarbocyanine (DiI). The core of VLDL particles was traced by