Disucinimidilo glutarato, 97%, Thermo Scientific Chemicals
Disucinimidilo glutarato, 97%, Thermo Scientific Chemicals
Disucinimidilo glutarato, 97%, Thermo Scientific Chemicals
Disucinimidilo glutarato, 97%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Disucinimidilo glutarato, 97%, Thermo Scientific Chemicals

CAS: 79642-50-5 | C13H14N2O8 | 326.26 g/mol
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Cantidad:
100 mg
500 mg
Número de catálogo H58208.ME
también denominado H58208-ME
Precio (USD)
-
Cantidad:
500 mg
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Identificadores químicos
CAS79642-50-5
IUPAC Namebis(2,5-dioxopyrrolidin-1-yl) pentanedioate
Molecular FormulaC13H14N2O8
InChI KeyLNQHREYHFRFJAU-UHFFFAOYSA-N
SMILESO=C(CCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O
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EspecificacionesSpecification SheetHoja de especificaciones
Appearance (Color)White to cream
FormCrystals or crystalline powder or powder
Assay from Suppliers CofA≥96.0% (TLC)
Identification (FTIR)Conforms
Melting Point130-136°C
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Disuccinimidyl glutarate is used as a membrane-soluble, amine-reactive N-hydroxysuccinamide ester-based homobifunctional crosslinking reagent. It is a homobifunctionla cross-linking reagent, for ex. isolation of the insulin receptor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Aplicaciones
El disucinimidilo glutarato se utiliza como reactivo entrecruzador homofuncional basado en éster de N-hidroxisucinamida soluble en membrana. Es un reactivo de entrecruzamiento homobifuncional, por ejemplo, para el aislamiento del receptor de insulina.

Solubilidad
Soluble en dimetilsulfóxido y dimetilformamida. Parcialmente soluble en agua.

Notas
Sensible a la humedad. Almacenar en lugar fresco. Incompatible con agentes oxidantes fuertes.
RUO – Research Use Only

General References:

  1. Morioka, T.; Loik, N. D.; Hipolito, C. J.; Goto, Y.; Suga, H. Selection-based discovery of macrocyclic peptides for the next generation therapeutics. Curr. Opin. Chem. Biol. 2015, 26, 34-41.
  2. Smaldone, G.; Diana, D.; Pollegioni, L.; Di Gaetano, S.; Fattorusso, R.; Pedone, E. Insight into conformational modification of alpha-synuclein in the presence of neuronal whole cells and of their isolated membranes. FEBS Lett. 2015, 589 (7), 798-804.