Clorhidrato de tiamina, Thermo Scientific Chemicals

Un tinte intercalante

Número de catálogo	Cantidad
J60048.14 también denominado J60048-14	25 g

Número de catálogo J60048.14

también denominado J60048-14

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Identificadores químicos

CAS8063-24-9

IUPAC Name3,6-diamino-10-methylacridin-10-ium acridine-3,6-diamine dihydrochloride chloride

Molecular FormulaC27H27Cl3N6

InChI KeyMKLTXAHQKDVBLY-UHFFFAOYSA-N

SMILESCl.Cl.[Cl-].NC1=CC2=NC3=CC(N)=CC=C3C=C2C=C1.C[N+]1=C2C=C(N)C=CC2=CC2=CC=C(N)C=C12

Especificaciones Specification Sheet

Loss on Drying6.5% max.

Sulfated Ash1.0% max.

Assay (Argentometric Titration)98.5% to 105%

Acriflavine Hydrochloride acts as an intercalating dye and also reported to inhibit mitochondriogenesis. It is an antiseptic and has been used in applications for dual fluorescence analysis of cellular DNA and protein simultaneously.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Aplicaciones
El clorhidrato de acriflavina actúa como un colorante intercalante y también se ha documentado que inhibe la mitocondriogénesis. Es un antiséptico y se ha utilizado en aplicaciones para el análisis de doble fluorescencia del ADN celular y proteínas simultáneamente.

Solubilidad
Soluble en agua, dimetilsulfóxido y metanol.

Notas
Una mezcla de cloruro de 3,6-diamino-10-metilacridinio y 3,6-diaminoacridina.

RUO – Research Use Only

General References:

Santiago Ramón-García et. al. Functional and genetic characterization of the tap efflux pump in Mycobacterium bovis BCG. Antimicrobial Agents and Chemotherapy, 2012, 56(4), 2074-2083.
Saadia Hassan et. al. Novel activity of acriflavine against colorectal cancer tumor cells. Cancer Science, 2011,102(12), 2206-2213.