Angiotensina I (humana), Thermo Scientific Chemicals

CAS: 484-42-4 | C62H89N17O14 | 1296.50 g/mol

Número de catálogo	Cantidad
J62102.LB0 también denominado J62102-#0	5 mg

Número de catálogo J62102.LB0

también denominado J62102-#0

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Identificadores químicos

CAS484-42-4

IUPAC Name(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-5-[(diaminomethylidene)amino]pentanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanamido]-3-(1H-imidazol-5-yl)propanamido]-4-methylpentanoic acid

Molecular FormulaC62H89N17O14

InChI KeyORWYRWWVDCYOMK-HBZPZAIKSA-N

SMILESCC[C@H](C)[C@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC(C)C)C(O)=O

Especificaciones Specification Sheet

Appearance (Color)White to off-white

FormPowder or crystals or crystalline powder

Assay≥95.0%

Mass SpecConforms

Angiotensin I (human) stimulates the release of aldosterone, another hormone, from the adrenal cortex. It acts as a precursor to angiotensin II. It acts as endogenous peptide substrate for angiotensin converting enzyme (ACE), precursor to the vasoconstrictor peptide angiotensin II

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Aplicaciones
La angiotensina I (humana) estimula la liberación de aldosterona, otra hormona, de la corteza suprarrenal. Actúa como precursor de la angiotensina II. Actúa como sustrato péptido endógeno para la enzima convertidora de angiotensina (ACE), precursor del péptido vasoconstrictor angiotensina II.

Solubilidad
Soluble en 1 mg/ml en agua.

Notas
Proteger del calor. Incompatible con el calor y los agentes oxidantes. Almacenar a 4 °C.

RUO – Research Use Only

General References:

K Manabe; H Shirahase; H Usui; K Kurahashi and M Fujiwara. Endothelium-dependent contractions induced by angiotensin I and angiotensin II in canine cerebral artery. JPET. 1989, 251, (1), 317-320.
Erdös EG; Skidgel RA. Renal metabolism of angiotensin I and II. Kidney International. Supplement. 1990, 30, S24-S27.