Cloroformato de 4,5-dimetoxi-2-nitrobencilo, 97 %, Thermo Scientific Chemicals

CAS: 42855-00-5 | C10H10ClNO6 | 275.641 g/mol

Número de catálogo	Cantidad
L14167.MD también denominado L14167-MD	250 mg

Número de catálogo L14167.MD

también denominado L14167-MD

Precio (USD)

Cantidad:

250 mg

Pedido a granel o personalizado

Identificadores químicos

CAS42855-00-5

IUPAC Name(4,5-dimethoxy-2-nitrophenyl)methyl carbonochloridate

Molecular FormulaC10H10ClNO6

InChI KeyRWWPKIOWBQFXEE-UHFFFAOYSA-N

SMILESCOC1=CC(COC(Cl)=O)=C(C=C1OC)[N+]([O-])=O

Especificaciones Specification Sheet

Appearance (Color)White to cream to yellow to orange to brown

FormCrystals or powder or crystalline powder

Assay (Titration ex Chloride)≥96.0 to ≤104.0%

Identification (FTIR)Conforms

4,5-Dimethoxy-2-nitrobenzyl chloroformate is used as a reagent for protection of amines, for use in N-protection of bases in nucleotide synthesis, photochemical protecting groups in organic synthesis. It is used as pharmaceutical intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Aplicaciones
El cloroformato de 4,5-dimetoxi-2-nitrobencilo se utiliza como reactivo para la protección de aminas, para el uso en N-protección de bases en la síntesis de nucleótidos, grupos protectores fotoquímicos en la síntesis orgánica. Se utiliza como intermedio farmacéutico.

Solubilidad
Soluble en metanol y acetona. Reacciona con el agua.

Notas
Sensible a la luz y a la humedad. Almacenar alejado de agentes oxidantes, luz, agua/humedad, calor y bases.

RUO – Research Use Only

General References:

P Roy, Z Rajfur; D Jones; G Marriott; L Loew; K Jacobson. Local photorelease of caged thymosin beta4 in locomoting keratocytes causes cell turning. Journal of Cell Biology. 2001, 153, (5), 1035-1048.
Adam Frankel; Steven W Millward; Richard W Roberts. Encodamers: Unnatural Peptide Oligomers Encoded in RNA. Chemistry & Biology. 2003, 10, (11), 1043-1050.
Reagent for protection of amines. The group is readily cleaved photolytically: Tetrahedron Lett., 29, 65 (1988). For use in N-protection of bases in nucleotide synthesis, see: J. Org. Chem., 64, 6319 (1999). For reviews of photochemical protecting groups in organic synthesis, see: Synthesis, 1 (1980); Org. Photochem., 9, 225 (1987).