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X1 Upgrade for ArrayScan™ VTI HCS Reader
Citas y referencias (242)
Thermo Scientific™

X1 Upgrade for ArrayScan™ VTI HCS Reader

The Thermo Scientific™ X1 Upgrade ArrayScan™ VTI HCS Reader takes a current Thermo Scientific ArrayScan™ VTI HCS Reader (600 andMás información
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Número de catálogoPara utilizar con (equipo)
N01X1SHTLASArrayScan VTI HCA Reader
Número de catálogo N01X1SHTLAS
Precio (USD)
-
Para utilizar con (equipo):
ArrayScan VTI HCA Reader
The Thermo Scientific™ X1 Upgrade ArrayScan™ VTI HCS Reader takes a current Thermo Scientific ArrayScan™ VTI HCS Reader (600 and 700 series) up to the latest image capture technology with the new X1 large field of view camera and. The Photometrics X1 CCD camera boasts a 14-bit dynamic range; 2208x2208 pixel array; 4.54 micron pixel size; and 75% peak Quantum Efficiency (QE) to provide high resolution images to the Thermo Scientific™ HCS Studio™ Cell Analysis Software, and ultimately to a relational database for secure storage and access.

Features of the X1 Upgrade for ArrayScan VTI HCS Reader:

• High sensitivity—By harnessing the photon-collecting power of the Sony™ SuperHAD microlens architecture, the X1 camera becomes ultra-sensitive without sacrificing resolution (4.5μm/pixel).
• See more in every image—The cutting-edge Photometrics X1 CCD camera with the enlarged field of view and 4.54 μm pixel size.
• Hardware designed for high throughput—Processing of the data and images from the X1 camera is optimized with a powerful Windows 7, 64-bit PC with a quad core processor.
• HCS Studio™ Cell Analysis Software is the integrated instrument control, visualization and analysis software package for novice to advanced users.
• Features Thermo Scientific™ Store Express Image and Database Software using a 10GB SQL™ database

Key Technological Features:

• High-resolution, thermo-electrically cooled to 0°C; 14-bit dynamic range; 2208x2208 pixel array; 4.54 micron pixel size; 75% peak Quantum Efficiency (QE); USB 2.0 (no additional CameraLink or FireWire Cards needed); 1x1, 2x2 or 4x4 binning options
• Binning option applied before digitization, which reduces read noise and provides for a 4:1 signal-to-noise ratio
• Larger imaging chip (2208 x 2208 px.)
• Sony SuperHAD microlens architecture for light collection
• Windows 7 Professional 64Bit Cube Computer with minimum quad core 3.7 GHz processor, 32GB RAM, and 500GB Hard Drive space for local images and data for instrument

Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.

Especificaciones
Para utilizar con (equipo)ArrayScan VTI HCA Reader
Línea de productosArrayScan
Unit Size1 each

Citations & References (242)

Citations & References
Abstract
HIV-1 transactivator protein induction of suppressor of cytokine signaling-2 contributes to dysregulation of IFN{gamma} signaling.
Authors:Cheng SM, Li JC, Lin SS, Lee DC, Liu L, Chen Z, Lau AS,
Journal:Blood
PubMed ID:19279332
HIV infection remains a worldwide threat. HIV-1 transactivator protein Tat is one of the retroviral proteins identified as a key immunomodulator in AIDS pathogenesis. Although the primary function of Tat is to regulate HIV-1 replication in the infected cell, it also dysregulates cytokine production resulting in perturbation of the host ... More
Multiple roles for the receptor tyrosine kinase axl in tumor formation.
Authors:Holland SJ, Powell MJ, Franci C, Chan EW, Friera AM, Atchison RE, McLaughlin J, Swift SE, Pali ES, Yam G, Wong S, Lasaga J, Shen MR, Yu S, Xu W, Hitoshi Y, Bogenberger J, Nör JE, Payan DG, Lorens JB,
Journal:Cancer Res
PubMed ID:16230391
A focus of contemporary cancer therapeutic development is the targeting of both the transformed cell and the supporting cellular microenvironment. Cell migration is a fundamental cellular behavior required for the complex interplay between multiple cell types necessary for tumor development. We therefore developed a novel retroviral-based screening technology in primary ... More
eIF4E activation is commonly elevated in advanced human prostate cancers and significantly related to reduced patient survival.
Authors:Graff JR, Konicek BW, Lynch RL, Dumstorf CA, Dowless MS, McNulty AM, Parsons SH, Brail LH, Colligan BM, Koop JW, Hurst BM, Deddens JA, Neubauer BL, Stancato LF, Carter HW, Douglass LE, Carter JH,
Journal:Cancer Res
PubMed ID:19383915
Elevated eukaryotic translation initiation factor 4E (eIF4E) function induces malignancy in experimental models by selectively enhancing translation of key malignancy-related mRNAs (c-myc and BCL-2). eIF4E activation may reflect increased eIF4E expression or phosphorylation of its inhibitory binding proteins (4E-BP). By immunohistochemical analyses of 148 tissues from 89 prostate cancer patients, ... More
Complex N-glycan and metabolic control in tumor cells.
Authors:Mendelsohn R, Cheung P, Berger L, Partridge E, Lau K, Datti A, Pawling J, Dennis JW,
Journal:Cancer Res
PubMed ID:17942907
Golgi beta1,6N-acetylglucosaminyltransferase V (Mgat5) produces beta1,6GlcNAc-branched complex N-glycans on cell surface glycoproteins that bind to galectins and promote surface residency of glycoproteins, including cytokine receptors. Carcinoma cells from polyomavirus middle T (PyMT) transgenic mice on a Mgat5-/- background have reduced surface levels of epidermal growth factor (EGF) and transforming growth ... More
Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation.
Authors:Joshi B, Bastiani M, Strugnell SS, Boscher C, Parton RG, Nabi IR,
Journal:J Cell Biol
PubMed ID:23091071
'Caveolin-1 (Cav1) is an essential component of caveolae whose Src kinase-dependent phosphorylation on tyrosine 14 (Y14) is associated with regulation of focal adhesion dynamics. However, the relationship between these disparate functions remains to be elucidated. Caveola biogenesis requires expression of both Cav1 and cavin-1, but Cav1Y14 phosphorylation is dispensable. In ... More
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