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Citas y referencias (64)
Invitrogen™
Colesterol NBD (22-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-il)amino)-23,24-bisnor-5-colen-3β-ol)
Este analógico fluorescente, el colesterol NBD, es una sonda sensible al medio ambiente que se localiza en el interior deMás información
| Número de catálogo | Cantidad |
|---|---|
| N1148 | 10 mg |
Número de catálogo N1148
Precio (USD)
716,04
Each
Cantidad:
10 mg
Precio (USD)
716,04
Each
Este analógico fluorescente, el colesterol NBD, es una sonda sensible al medio ambiente que se localiza en el interior de la membrana y es útil para investigar los procesos de transporte de lípidos, así como las interacciones entre lípidos y proteínas.
Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.
Especificaciones
Nombre del producto químico o materialAnálogos del colesterol
Excitación/emisión469/537 nm
Almacenamiento recomendadoAlmacenar a temperatura ambiente y proteger de la luz.
Forma físicaSolid
Línea de productosInvitrogen
Cantidad10 mg
Unit SizeEach
Citations & References (64)
Citations & References
Abstract
Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.
Journal:J Biol Chem
PubMed ID:15671032
'NPC1L1, a recently identified relative of Niemann-Pick C1, was characterized to determine its subcellular location and potential function(s). NPC1L1 was highly expressed in HepG2 cells and localized in a subcellular vesicular compartment rich in the small GTPase Rab5. mRNA expression profiling revealed significant differences between mouse and man with highest
High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single- and multiphoton fluorescence approach.
Journal:J Biol Chem
PubMed ID:10777574
'Fluorescent sterols, dehydroergosterol and NBD-cholesterol, were used to examine high density lipoprotein-mediated cholesterol uptake and intracellular targeting in L-cell fibroblasts. The uptake, but not esterification or targeting to lipid droplets, of these sterols differed >100-fold, suggesting significant differences in uptake pathways. NBD-cholesterol uptake kinetics and lipoprotein specificity reflected high density
Lipid binding to sterol carrier protein-2 is inhibited by ethanol.
Journal:Biochim Biophys Acta
PubMed ID:9931423
'Sterol carrier protein-2 (SCP-2) is an intracellular lipid carrier protein that binds cholesterol, phospholipids, fatty acids and other ligands. It has been reported that expression of SCP-2 was increased in brain nerve endings or synaptosomes of chronic ethanol-treated mice and it was shown that cholesterol homeostasis was altered in brain
Formation of membrane domains created during the budding of vesicular stomatitis virus. A model for selective lipid and protein sorting in biological membranes.
Journal:Biochemistry
PubMed ID:7543280
'Vesicular stomatitis virus buds from domains of the plasma membrane that have a unique protein and lipid composition. Fluorescence digital imaging microscopy and resonance energy transfer were used to determine how the two viral envelope-associated proteins, the G and the M proteins, could alter the lateral distribution of lipids in
Membrane properties of D-erythro-N-acyl sphingomyelins and their corresponding dihydro species.
Journal:Biophys J
PubMed ID:11325733
'We have prepared acyl chain-defined D-erythro-sphingomyelins and D-erythro-dihydrosphingomyelins and compared their properties in monolayer and bilayer membranes. Surface pressure/molecular area isotherms of D-erythro-N-16:0-sphingomyelin (16:0-SM) and D-erythro-N-16:0-dihydrosphingomyelin (16:0-DHSM) show very similar packing properties, except that the expanded-to-condensed phase transition (crystallization) occurs at a lower surface pressure for 16:0-DHSM. The measured surface