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Citations & References (13)
Thermo Scientific™
CellInsight™ CX5 High Content Screening (HCS) Platform
The Thermo Scientific™ CellInsight™ CX5 High Content Screening (HCS) Platform is a fast, simple-to operate, automated cellular imaging and analysisRead more
| Catalog Number | Quantity |
|---|---|
| CX51110 | 1 each |
Catalog number CX51110
Price (BRL)
-
Quantity:
1 each
The Thermo Scientific™ CellInsight™ CX5 High Content Screening (HCS) Platform is a fast, simple-to operate, automated cellular imaging and analysis benchtop platform designed for quantitative microscopy. The CellInsight CX5 HCS Platform offers a cost effective, but powerful way to quickly automate quantitative cellular and subcellular imaging.
Features of the CellInsight CX5 HCS Platform
• Easy to Use—quickly build and optimize image-based assays with included Thermo Scientific™ HCS Studio™ Cell Analysis Software
• Flexible—designed to work with or without fluorescent labeling: The CellInsight CX5 HCS Platform can use transmitted light, as well as fluorescence, to allow users to focus on visible and/or fluorescent targets
• Affordable—automated high content imaging for all budgets
• High quality optics—Light sources, lenses, filters, and CCD detector from the top names in imaging. The five color light engine insures accuracy and stability of source lighting.
• Virtually maintenance–free operation due to state-of-the-art design and construction.
• Performance—scan and analyze a 96-well plate in under four minutes
• Compact—fits on a bench and is less than 2 ft. on all sides
Capabilities:
• Make intracellular to multicellular morphology measurements while measuring intensity of specific reporter molecules.
• Collect only the images and data you select and make multiple measurements per object, over time, if desired
• Measure subpopulations and reject undesired objects automatically
• Comprehensive pre-validated and user configurable image analysis without user scripting or programming
• Exploratory assay development tools and specific biology optimized tools built into the HCS Studio™ Cell Analysis Software
• Define biological thresholds for outputs based on control populations
• Ability to create multi-parameter gates from individual output measurements
Hardware and Software:
• Stable, reliable light source reduces variability, increases data quality, and decreases operating costs
• Fluorescence options which include near-IR wavelength and compatibility with many common fluorochromes and fluorescent proteins
• • Proprietary Thermo Scientific™ AccuFocus™ System is fast, yet flexible, for imaging cells, organelles, and low contrast targets
• Unique intelligent acQuisition (iQ) real time analysis feedback to optimize image collection and data quality
• HCS Studio Cell Analysis Software is an integrated instrument control, visualization and analysis software package for novice to advanced users
• Features Thermo Scientific™ Store Express Image and Database Software using a 10GB SQL™ database
• Software output features image/data portability so results can be imported into third-party software for documentation
• Compatible with SBS standard microplates (6-1536 well) and slides
Compatible with Thermo Scientific™ Orbitor RS Plate Mover and other Thermo Scientific™ Laboratory Automation Solutions
Features of the CellInsight CX5 HCS Platform
• Easy to Use—quickly build and optimize image-based assays with included Thermo Scientific™ HCS Studio™ Cell Analysis Software
• Flexible—designed to work with or without fluorescent labeling: The CellInsight CX5 HCS Platform can use transmitted light, as well as fluorescence, to allow users to focus on visible and/or fluorescent targets
• Affordable—automated high content imaging for all budgets
• High quality optics—Light sources, lenses, filters, and CCD detector from the top names in imaging. The five color light engine insures accuracy and stability of source lighting.
• Virtually maintenance–free operation due to state-of-the-art design and construction.
• Performance—scan and analyze a 96-well plate in under four minutes
• Compact—fits on a bench and is less than 2 ft. on all sides
Capabilities:
• Make intracellular to multicellular morphology measurements while measuring intensity of specific reporter molecules.
• Collect only the images and data you select and make multiple measurements per object, over time, if desired
• Measure subpopulations and reject undesired objects automatically
• Comprehensive pre-validated and user configurable image analysis without user scripting or programming
• Exploratory assay development tools and specific biology optimized tools built into the HCS Studio™ Cell Analysis Software
• Define biological thresholds for outputs based on control populations
• Ability to create multi-parameter gates from individual output measurements
Hardware and Software:
• Stable, reliable light source reduces variability, increases data quality, and decreases operating costs
• Fluorescence options which include near-IR wavelength and compatibility with many common fluorochromes and fluorescent proteins
• • Proprietary Thermo Scientific™ AccuFocus™ System is fast, yet flexible, for imaging cells, organelles, and low contrast targets
• Unique intelligent acQuisition (iQ) real time analysis feedback to optimize image collection and data quality
• HCS Studio Cell Analysis Software is an integrated instrument control, visualization and analysis software package for novice to advanced users
• Features Thermo Scientific™ Store Express Image and Database Software using a 10GB SQL™ database
• Software output features image/data portability so results can be imported into third-party software for documentation
• Compatible with SBS standard microplates (6-1536 well) and slides
Compatible with Thermo Scientific™ Orbitor RS Plate Mover and other Thermo Scientific™ Laboratory Automation Solutions
For Research Use Only. Not for use in diagnostic procedures.
Specifications
ColorGreen, Blue, Near-Infrared, Far-Red, Red
Data OutputsJPG Files, TIFF Files, PNG Files, C01, BMP, BIN, PZFX, ICE, GIF Files, DIB, CSV, FCS 3.1, XLSX
DescriptionCeLLInsight™ CX5 High Content Screening Platform with HCS Studio Cell Analysis Software and Store Express
Detection MethodBrightfield, Fluorescence
Dimensions41.4 cm (16.3 in) (W) x 37.2 cm (14.6 in) (H) x 59.4 cm (23.4 in) (D)
Display24in High-resolution widescreen monitor
For Use With (Equipment)Thermo Scientific™ Orbitor™ RS Plate Mover
FormatSlide(s), 96-well plate, 384-well plate, 6-well plate, 1536-well plate, 8 wells, 24-well plate
High-throughput CompatibilityHigh-throughput Compatible, Multiplexing, Automated Protocols
Memory8GB RAM
ObjectivesAdditional Objectives Available, Low and High NA, Single Position 2x-20x
Operating EnvironmentPermissible ambient temperature range during operation : + 18 deg C to + 25 deg C, Permissible relative humidity during operation (noncondensing): > 75% at 30 deg C
Operating SystemWindows 7
OpticsCCD Camera, LED, solid-state 5-color light engine
PCWindows 7™ 64-bit PC with quad core 3.7GHz processor, 8GB RAM, and 500GB Hard Drive
Quantity1 each
Software CompatibilityThermo Scientific™ Store™ Image and Database Management Software, Thermo Scientific™ HCS Studio™ Cell Analysis Software
Voltage120V
Wattage300 W
Wavelength740⁄809, 560⁄607, 485⁄521, 386⁄440, 650⁄694
Weight (Metric)45 kg
Product LineCellInsight
Unit SizeEach
Frequently asked questions (FAQs)
Who do I contact if I have issues with my CellInsight systems or ArrayScan System?
For high-content analysis (HCA)/high-content screening (HCS), what are the main differences between the CellInsight CX5, CX7, and ArrayScan systems?
Citations & References (13)
Citations & References
Abstract
Pumpless platform for high-throughput dynamic multicellular culture and chemosensitivity evaluation.
Journal:Lab Chip
PubMed ID:30547180
'We report here a novel pumpless, 96-well plate-based platform for high-throughput dynamic multicellular culture and chemosensitivity evaluation. A gravity-driven flow strategy was developed to generate and sustain the flow rate of culture medium within 10% in the platform''s 20 culture chambers. The ability of the platform to generate and sustain
Microscopy-Based Automated Live Cell Screening for Small Molecules That Affect Ciliation.
Journal:Front Genet
PubMed ID:30809247
'The primary monocilium, or cilium, is a single antenna-like organelle that protrudes from the surface of most mammalian cell types, and serves as a signaling hub. Mutations of cilia-associated genes result in severe genetic disorders termed ciliopathies. Among these, the most common is autosomal dominant polycystic kidney disease (ADPKD); less
In Vitro Screening Platforms for Identifying Autophagy Modulators in Mammalian Cells.
Journal:Methods Mol Biol
PubMed ID:30610712
'Autophagy is a vital homeostatic pathway essential for cellular survival and human health. It primarily functions as an intracellular degradation process for the turnover of aggregation-prone proteins and unwanted organelles. Dysregulation of autophagy underlying diverse human diseases reduces cell viability, whereas stimulation of autophagy is cytoprotective in a number of
Epigenetic regulation of diabetogenic adipose morphology.
Journal:Mol Metab
PubMed ID:31031182
'Hypertrophic white adipose tissue (WAT) morphology is associated with insulin resistance and type 2 diabetes. The mechanisms governing hyperplastic versus hypertrophic WAT expansion are poorly understood. We assessed if epigenetic modifications in adipocytes are associated with hypertrophic adipose morphology. A subset of genes with differentially methylated CpG-sites (DMS) in the
The effect of rho kinase inhibition on morphological and electrophysiological maturity in iPSC-derived neurons.
Journal:Cell Tissue Res
PubMed ID:30406823
'Induced pluripotent stem cell (iPSC)-derived neurons permit the study of neurogenesis and neurological disease in a human setting. However, the electrophysiological properties of iPSC-derived neurons are consistent with those observed in immature cortical neurons, including a high membrane resistance depolarized resting membrane potential and immature firing properties, limiting their use