Search
Citations & References (27)
Invitrogen™
FluoZin™-3, Tetrapotassium Salt, cell impermeant
The FluoZin™-3 indicator is a Zn2+-selective indicator with a structure that resembles fluo-4. FluoZin™-3 exhibits high Zn2+-binding affinity that isRead more
| Catalog Number | Quantity |
|---|---|
| F24194 | 500 μg |
Catalog number F24194
Price (BRL)
2.830,93
Each
Quantity:
500 μg
Price (BRL)
2.830,93
Each
The FluoZin™-3 indicator is a Zn2+-selective indicator with a structure that resembles fluo-4. FluoZin™-3 exhibits high Zn2+-binding affinity that is unperturbed by Ca2+ concentrations up to at least 1 μM. In addition, FluoZin™-3 exhibits a >50-fold increase in fluorescence in response to saturating levels of Zn2+. Although imaging applications of FluoZin™-3 are predominant, cell-based microplate assays and flow cytometry protocols have also been developed. FluoZin™-3 indicator is available in a cell-permeant and a cell-impermeant form.
Learn more about ion indicators including calcium, potassium, pH, and membrane potential indicators ›
Fluorescent Zinc Indicators Specifications:
• Label (Ex/Em): FluoZin™-3 (∼494/516 nm)
• Kd (Zn2+) (in buffer): ∼15 nM
• Lyophilized product may be dissolved in distilled water or aqueous buffer for use
• Product is typically loaded into cellsusing microinjection or diffusion from patch pipette
Find Fluorescent Indicators for Zinc and Other Metal Ions
We offer a number of fluorescent indicators to determine polyvalent cation concentrations inside cells, to follow metal ion transport through ion channels, to make measurements in environmental samples, and more. Review Fluorescent Indicators for Zn2+ and Other Metal Ions—Section 19.7 in the Molecular Probes™ Handbook for more information on these products.
For Research Use Only. Not for human or animal therapeutic or diagnostic use.
Learn more about ion indicators including calcium, potassium, pH, and membrane potential indicators ›
Fluorescent Zinc Indicators Specifications:
• Label (Ex/Em): FluoZin™-3 (∼494/516 nm)
• Kd (Zn2+) (in buffer): ∼15 nM
• Lyophilized product may be dissolved in distilled water or aqueous buffer for use
• Product is typically loaded into cellsusing microinjection or diffusion from patch pipette
Find Fluorescent Indicators for Zinc and Other Metal Ions
We offer a number of fluorescent indicators to determine polyvalent cation concentrations inside cells, to follow metal ion transport through ion channels, to make measurements in environmental samples, and more. Review Fluorescent Indicators for Zn2+ and Other Metal Ions—Section 19.7 in the Molecular Probes™ Handbook for more information on these products.
For Research Use Only. Not for human or animal therapeutic or diagnostic use.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Detection MethodFluorescence
Dye TypeZinc Indicator
Quantity500 μg
Shipping ConditionRoom Temperature
For Use With (Equipment)Fluorescence Microscope
Product LineFluoZin
Product TypeZinc Indicator
Unit SizeEach
Contents & Storage
Store in freezer -5°C to -30°C and protect from light.
Citations & References (27)
Citations & References
Abstract
Uncoupling of the base excision and nucleotide incision repair pathways reveals their respective biological roles.
Journal:Proc Natl Acad Sci U S A
PubMed ID:16473948
'The multifunctional DNA repair enzymes apurinic/apyrimidinic (AP) endonucleases cleave DNA at AP sites and 3''-blocking moieties generated by DNA glycosylases in the base excision repair pathway. Alternatively, in the nucleotide incision repair (NIR) pathway, the same AP endonucleases incise DNA 5'' of a number of oxidatively damaged bases. At present,
Fluorescence imaging study of extracellular zinc at the hippocampal mossy fiber synapse.
Journal:Neurosci Lett
PubMed ID:17485170
'Although synaptically released, vesicular Zn(2+) has been proposed to play a neuromodulatory or neuronal signaling role at the mossy fiber-CA3 synapse, Zn(2+) release remains controversial, especially when detected using fluorescent imaging. In the present study, we investigated synaptically released Zn(2+) at the mossy fiber (MF) synapse in rat hippocampal slices
Determining zinc with commonly used calcium and zinc fluorescent indicators, a question on calcium signals.
Journal:Cell Calcium
PubMed ID:16764924
'Investigations into the roles of Ca(2+) and Zn(2+) in cell biology have been facilitated by the development of sensitive fluorometric probes that have enabled the measurement of Ca(2+) or Zn(2+) in both extracellular and intracellular environments. It is critical to be aware of the specificity and relative selectivity of a
Integration of multianalyte sensing functions on a capillary-assembled microchip: simultaneous determination of ion concentrations and enzymatic activities by a "drop-and-sip" technique.
Journal:Anal Chem
PubMed ID:17263315
'A general and simple implementation of simultaneous multiparametric sensing in a single microchip is presented by using a capillary-assembled microchip (CAs-CHIP) integrated with the plural different reagent-release capillaries (RRCs), acting as various biochemical sensors. A novel "drop-and-sip" technique of fluid handling is performed with a microliter droplet of a model
Dual nanomolar and picomolar Zn(II) binding properties of metallothionein.
Journal:J Am Chem Soc
PubMed ID:17696343
'Each of the seven Zn(II) ions in the Zn(3)S(9) and Zn(4)S(11) clusters of human metallothionein is in a tetrathiolate coordination environment. Yet analysis of Zn(II) association with thionein, the apoprotein, and analysis of Zn(II) dissociation from metallothionein using the fluorescent chelating agents FluoZin-3 and RhodZin-3 reveal at least three classes