CTS™ DynaMag™ Magnet
CTS™ DynaMag™ Magnet
Gibco™

CTS™ DynaMag™ Magnet

The CTS™ DynaMag™ Magnet is suitable for use with commercially available sterile blood/culture bags, tubing, and connectors.Benefits:• Ideal for magneticLeia mais
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Número do catálogoQuantity
121021 Each
Número do catálogo 12102
Preço (BRL)
285.995,09
Each
Adicionar ao carrinho
Quantity:
1 Each
Preço (BRL)
285.995,09
Each
Adicionar ao carrinho
The CTS™ DynaMag™ Magnet is suitable for use with commercially available sterile blood/culture bags, tubing, and connectors.

Benefits:
• Ideal for magnetic isolation in closed, sterile blood bags
• Scalable volumes: 50 to 330 mL in static separations and >10 L in continuous flow separations following T-cell expansion protocols
• Residual beads that escape initial magnetic capture are retained on a secondary magnet

Applications:
• Positive isolation of CD3+ T-cells for subsequent stimulation/expansion with CTS™ Dynabeads™ CD3/CD28 and removal of CTS Dynabeads CD3/CD28 following T-cell expansion

The CTS DynaMag Magnet is intended for use with the CTS Dynabeads product portfolio in clinical research such as CTS Dynabeads CD3/CD28 (Cat. No. 40203D).
For Research Use or Manufacturing of Cell, Gene, or Tissue-Based Products. CAUTION: Not intended for direct administration into humans or animals.
Especificações
For Use With (Equipment)DynaMag™
Product LineCTS, DynaMag
Quantity1 Each
Research CategoryCell Therapy Research
Shipping ConditionRoom Temperature
Unit SizeEach
Conteúdo e armazenamento
The product contains: CTS DynaMag Magnet

Storage Conditions:
Protect the device from vibration and keep out of direct sunlight.

Frequently asked questions (FAQs)

What are the Gauss levels for the DynaMag-2 and DynaMag-Spin Magnets?

The DynaMag-2 Magnet is 3,500-3,700 minimum Gauss level and the DynaMag-Spin is 3,000-3,500 minimum Gauss level.

Find additional tips, troubleshooting help, and resources within our Protein Assays and Analysis Support Center.

What is the standard conversion of Gauss to Tesla units?

1 Tesla is equivalent to 10,000 Gauss. .

How can I clean my DynaMag magnet?

Spray and/or wipe the DynaMag magnet unit with one of the following cleaning agents:

- 70% (v/v) isopropyl alcohol
- 1% (v/v) sodium hypochlorite solution (bleach)
- 0.1 N HCl solution

Do not submerge the magnet unit in aqueous solutions and avoid prolonged exposure to water or aqueous solutions. Clean with a damp cloth and mild detergent when exposed to harsh solvents. Do not autoclave the magnet unit as heating the magnet to above 70 degrees C can destabilize the magnetic material, resulting in loss of magnetic strength.

What is the difference between the DynaMag-2 Magnet (Cat. No. 12321D) and DynaMag-Spin Magnet (Cat. No. 12320D)?

The DynaMag-2 Magnet can hold 16 standard 1.5 mL or 2 mL microcentrifuge tubes, while the DynaMag-Spin Magnet holds up to 6 standard 1.5 mL microcentrifuge tubes.

What is the definition of superparamagnetic, and what does this mean for my cell isolation application with Dynabeads magnetic beads?

Superparamagnetic means that the Dynabeads magnetic beads exhibit magnetic properties when placed within a magnetic field, but have no residual magnetism when removed from the magnetic field.

This means that your targeted cells, proteins, or nucleic acids are only subjected to magnetic forces during the time the beads are on the magnet. The beads do not aggregate, but remain evenly dispersed in suspension.

Find additional tips, troubleshooting help, and resources within our Dynabeads Cell Isolation and Expansion Support Center.

Citações e referências (2)

Citações e referências
Abstract
Manufacturing validation of biologically functional T cells targeted to CD19 antigen for autologous adoptive cell therapy.
Authors:Hollyman D, Stefanski J, Przybylowski M, Bartido S, Borquez-Ojeda O, Taylor C, Yeh R, Capacio V, Olszewska M, Hosey J, Sadelain M, Brentjens RJ, Rivière I,
Journal:J Immunother
PubMed ID:19238016
On the basis of promising preclinical data demonstrating the eradication of systemic B-cell malignancies by CD19-targeted T lymphocytes in vivo in severe combined immunodeficient-beige mouse models, we are launching phase I clinical trials in patients with chronic lymphocytic leukemia (CLL) and acute lymphoblastic leukemia. We present here the validation of ... More
Simplified process for the production of anti-CD19-CAR-engineered T cells.
Authors:Tumaini B, Lee DW, Lin T, Castiello L, Stroncek DF, Mackall C, Wayne A, Sabatino M,
Journal:
PubMed ID:23992830
Adoptive immunotherapy with the use of chimeric antigen receptor (CAR)-engineered T cells specific for CD19 has shown promising results for the treatment of B-cell lymphomas and leukemia. This therapy involves the transduction of autologous T cells with a viral vector and the subsequent cell expansion. We describe a new, simplified ... More