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2'-Fluoro-Bz-A Phosphoramidite, standard grade, 20-400 finish bottle
Thermo Scientific™

2'-Fluoro-Bz-A Phosphoramidite, standard grade, 20-400 finish bottle

2'-Fluoro-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-Fluoro protection, for use in oligonucleotideLeia mais
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Número do catálogoQuantity
27-1601-090.25 g
Número do catálogo 27-1601-09
Preço (BRL)
240,69
Each
Quantity:
0.25 g
Preço (BRL)
240,69
Each

2'-Fluoro-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

For Research Use Only. Not for use in diagnostic procedures.
Especificações
31P NMR Purity≥98%
Chemical Name or Material5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-fluoroadenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
DescriptionBase: A
Base Protection: Bz
For Use With (Application)Oligonucleotide synthesis
For Use With (Equipment)Expedite Synthesizers
FormPowder
FormatAmber bottle (20-400 finish neck style)
GradeStandard
Molecular FormulaC47H51FN7O7P
Molecular Weight (g/mol)875.92 g/mol
Nucleic Acid TypeRNA
Nucleoside TypeAdenosine (A)
Product Type2in-Fluoro-Bz-A CEP
Purity>98% (HPLC)
Quantity0.25 g
Reagent Features2in-Fluoro modified
Reagent TypePhosphoramidite
Shipping ConditionRoom Temperature
Unit SizeEach
Conteúdo e armazenamento
Store in freezer (at or below -20°C).