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Gibco™
CTS™ Detachable Dynabeads™ CD4
CTS Detachable Dynabeads CD4 for positive isolation of CD4+ T cells and active release of Dynabeads post-isolation.
| Número do catálogo | Quantity |
|---|---|
| A56994 | 15 mL vial |
Número do catálogo A56994
Preço (BRL)
-
Quantity:
15 mL vial
Gibco CTS Detachable Dynabeads CD4 are intended for ex vivo isolation of CD4+ T cell subsets. Combined with CTS Detachable Dynabeads Release Buffer (Cat. No. A5588301, A5588302, or A5588303), it is a first-of-its-kind cGMP cell selection technology with an active release mechanism for process development, clinical trial, and commercial manufacturing use. This product is also commonly used with CTS Detachable Dynabeads CD8 (Cat. No. A56995).
Features of CTS Detachable Dynabeads CD4 include:
- Empower users with process flexibility by allowing active release of beads from target cells at any time
- Optimize target cell purity and yield thanks to the active release mechanism that gives users more control
- Provide an automation-friendly solution by working directly with the CTS DynaCellect Magnetic Separation System
- Enable consistent performance in light of biological variability within the starting material
- Suitable for both autologous and allogeneic cell therapy manufacturing processes
These Detachable Dynabeads are intended for use with CTS Detachable Dynabeads Release Buffer, which has an active ingredient, biotin, that competitively displaces a biotin derivative on the surface of the beads. This proprietary mechanism allows users to achieve active release of the beads from target cells at any time within their process.
Based on a recommended 4-to-1 bead-to-target-cell ratio (not total nucleated cell number), one 15 mL vial can theoretically isolate up to 1.5 x 109 CD4+ T cells.
CTS Detachable Dynabeads also include a Drug Master File (DMF) to support cross-referencing in regulatory submissions prior to clinical trial and commercial manufacturing use.
For Research Use or Manufacturing of Cell, Gene, or Tissue-Based Products. CAUTION: Not intended for direct administration into humans or animals.
Especificações
Concentration4 x 108 beads/mL
For Use With (Equipment)CTS™ DynaCellect™ Magnetic Separation System
Product LineCTS Detachable Dynabeads
Purity or Quality GradeGMP-grade
Quantity15 mL vial
Shipping ConditionShips at 2°C to 8°C with wet (not frozen) gel packs. Vial must remain upright to keep beads in suspension.
Volume (Metric)15 mL
ColorBrown
Diameter (Metric)4.5 μm
MaterialPolystyrene
Product TypeCell Isolation Reagent
Unit SizeEach
Conteúdo e armazenamento
CTS™ Detachable Dynabeads™ CD4, 15 mL.
Store at 2°C to 8°C with vial upright to keep beads in suspension.
Store at 2°C to 8°C with vial upright to keep beads in suspension.