6-TAMRA (6-Carboxytetramethylrhodamine), single isomer

Name: 6-TAMRA (6-Carboxytetramethylrhodamine), single isomer
SKU: C6122

Tetramethylrhodamine (TMR, TRITC) has been a widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used inLeia mais

Número do catálogo C6122

conhecido também como C-6122

Preço (BRL)

Tetramethylrhodamine (TMR, TRITC) has been a widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry. Under the name TAMRA, the carboxylic acid of 6-TAMRA has also achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications.

For Research Use Only. Not for use in diagnostic procedures.

Especificações

Chemical ReactivityAmine

Label or DyeTAMRA™ Isomers, TMR (Tetramethylrhodamine)

Product Type6-TAMRA

Quantity10 mg

Reactive MoietyCarboxylic Acid

Shipping ConditionRoom Temperature

Label TypeClassic Dyes

Unit Size10 mg

Citações e referências (11)

Citações e referências

Abstract

Inter- and intramolecular fluorescence quenching of organic dyes by tryptophan.

Authors:Marmé N, Knemeyer JP, Sauer M, Wolfrum J

Journal:Bioconjug Chem

PubMed ID:14624626

'Steady-state and time-resolved fluorescence measurements were performed to elucidate the fluorescence quenching of oxazine, rhodamine, carbocyanine, and bora-diaza-indacene dyes by amino acids. Among the natural amino acids, tryptophan exhibits the most pronounced quenching efficiency. Especially, the red-absorbing dyes ATTO 655, ATTO 680, and the oxazine derivative MR 121 are strongly ... More

Toxicity of organic fluorophores used in molecular imaging: literature review.

Authors:Alford R, Simpson HM, Duberman J, Hill GC, Ogawa M, Regino C, Kobayashi H, Choyke PL,

Journal:Mol Imaging

PubMed ID:20003892

'Fluorophores are potentially useful for in vivo cancer diagnosis. Using relatively inexpensive and portable equipment, optical imaging with fluorophores permits real-time detection of cancer. However, fluorophores can be toxic and must be investigated before they can be administered safely to patients. A review of published literature on the toxicity of ... More

Synthesis and characterization of fluorescent ubiquitin derivatives as highly sensitive substrates for the deubiquitinating enzymes UCH-L3 and USP-2.

Authors:Tirat A, Schilb A, Riou V, Leder L, Gerhartz B, Zimmermann J, Worpenberg S, Eidhoff U, Freuler F, Stettler T, Mayr L, Ottl J, Leuenberger B, Filipuzzi I

Journal:Anal Biochem

PubMed ID:15963938

'Deubiquitinating enzymes (DUBs) catalyze the removal of attached ubiquitin molecules from amino groups of target proteins. The large family of DUBs plays an important role in the regulation of the intracellular homeostasis of different proteins and influences therefore key events such as cell division, apoptosis, etc. The DUB family members ... More

Extending the applicability of carboxyfluorescein in solid-phase synthesis.

Authors:Fischer R, Mader O, Jung G, Brock R

Journal:Bioconjug Chem

PubMed ID:12757391

'Optimized coupling protocols are presented for the efficient and automated generation of carboxyfluorescein-labeled peptides. Side products, generated when applying earlier protocols for the in situ activation of carboxyfluorescein, were eliminated by a simple procedure, yielding highly pure fluorescent peptides and minimizing postsynthesis workup. For the cost-efficient labeling of large compound ... More

Pathway for polyarginine entry into mammalian cells.

Authors:Fuchs SM, Raines RT,

Journal:Biochemistry

PubMed ID:14992581

Cationic peptides known as protein transduction domains (PTDs) provide a means to deliver molecules into mammalian cells. Here, nonaarginine (R(9)), the most efficacious of known PTDs, is used to elucidate the pathway for PTD internalization. Although R(9) is found in the cytosol as well as the nucleolus when cells are ... More

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