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Proteome Discoverer™ Software
Thermo Scientific™

Proteome Discoverer™ Software

Simplify and enable a wide range of proteomics workflows, from identification to PTM analysis to isobaric mass tagging for quantitation with intelligent innovations.
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Número do catálogoIncludes
PROTEOMEDISC3Proteome Discoverer 3.3
CSW0064768CHIMERYS Lite 1 year
CSW0064769CHIMERYS Lite 1 year
CSW0064771CHIMERYS Full 1 year
CSW0064772CHIMERYS Plus 1 year
CSW0064773CHIMERYS Plus 1 year
CSW00647743.2 Upgrade from Base to Quan
Número do catálogo PROTEOMEDISC3
Preço (BRL)
-
Includes:
Proteome Discoverer 3.3
Identify and quantify peptides and proteins in complex biological samples using Thermo Scientific™ Proteome Discoverer™ software. Proteome Discoverer software simplifies a wide range of proteomics workflows, from protein and peptide identification to PTM analysis to isobaric mass tagging and both SILAC and label-free quantitation. It supports multiple database search algorithms and multiple dissociation techniques. Go beyond searching to discovering with intelligent INFERYS™ Rescoring and the CHIMERYS™ intelligent search algorithm by MSAID to substantially increase the number of unique peptide identifications.
Proteome Discoverer software supports multiple dissociation techniques, quantitation technologies, and database search algorithms for comprehensive protein identification, characterization, and quantitation.

 

Comprehensive

  • Streamlines your protein research data processing with flexible, built-in or customizable workflows
  • Find more with the intelligent INFERYS Rescoring and CHIMERYS algorithms
  • Supports multiple dissociation techniques (HCD, CID, ETD, and UVPD) for more complete coverage and confident identification of PTMs
  • Supports isobaric mass tagging (TMT, iTRAQ), isotopic labeling (SILAC), and label-free quantification
  • Validates peptide and protein IDs with false discovery rate (FDR)
  • Accommodates nodes for top-down (ProsightPD) and structural biology and cross-linking analysis (XL-MS)

Productive and Extensible

  • Automates data analysis and simplifies MSn data analysis through pre-built and customizable workflows
  • Includes study management for mapping of quantitation to biological information about the sample
  • Use results to refine data collection, such as exporting inclusion and exclusion lists for import directly into instrument methods
  • Illustrates biological context by automatically annotating identified proteins with GO classifications, PTM sites, and literature references from public databases
  • Facilitates data comparison, exchange, and verification with support for data standards developed by the HUPO Proteomics Standards Initiative (PSI)
  • Supports third party nodes for data processing and enables processing of large datasets
  • Fast, robust algorithms empowered by artificial intelligence for peak selection and peptide quantification to extract more information
  • Obtain reliable statistics and validate quantification results visually
Especificações
For Use With (Application)Proteomics
IncludesProteome Discoverer 3.3
TechniqueMS
TypeSoftware
Unit SizeEach

Frequently asked questions (FAQs)

How does Thermo Scientific Proteome Discoverer software support data interpretation and biological context?

Thermo Scientific Proteome Discoverer software includes tools to help interpret proteomics results and place them in a biological context. It provides hierarchical views linking proteins, peptides, and peptide-spectrum matches, along with interactive filtering and visualization tools such as heat maps and chromatograms. The software also supports biological annotation through gene ontology, protein family classification, and pathway analysis, helping users understand the functional relevance of identified proteins.

How does Thermo Scientific Proteome Discoverer software support quantitation and comparative analysis?

Thermo Scientific Proteome Discoverer software supports multiple quantitation strategies, including isobaric labeling approaches such as tandem mass tag (TMT) and TMTpro reagents, as well as label-free quantification methods. It enables comparative analysis across sample groups using statistical tools and visualizations such as principal component analysis, clustering, and volcano plots. The software also supports targeted quantitation workflows and allows users to organize study designs by mapping sample types and experimental variables for downstream analysis.

What types of proteomics workflows can Thermo Scientific Proteome Discoverer software support?

Thermo Scientific Proteome Discoverer software supports a range of proteomics workflows, including discovery-based and targeted approaches. Supported workflows include data-dependent acquisition (DDA), data-independent acquisition (DIA), and targeted methods such as parallel reaction monitoring (PRM) and SureQuant workflows. The software also supports applications such as post-translational modification analysis, cross-linking studies, and top-down proteomics, allowing users to adapt workflows to different experimental goals.

When should I use Thermo Scientific Proteome Discoverer software for proteomics data analysis?

Use Thermo Scientific Proteome Discoverer software when your laboratory needs a unified platform for both qualitative and quantitative proteomics data analysis. It is commonly used for peptide and protein identification, post-translational modification analysis, and quantitative workflows including isobaric labeling and label-free quantification. We recommend Proteome Discoverer software for laboratories working with complex proteomics datasets, multiple acquisition strategies, or workflows that benefit from integrated data processing and analysis within a single software environment.