SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)
SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)
Citas y referencias (4)
Thermo Scientific™

SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)

El SMPB Thermo Scientific Pierce es un entrecruzador de amina a sulfhidrilo que contiene grupos reactivos de éster NHS yMás información
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Número de catálogoCantidad
2241650 mg
Número de catálogo 22416
Precio (CLP)
-
Cantidad:
50 mg
El SMPB Thermo Scientific Pierce es un entrecruzador de amina a sulfhidrilo que contiene grupos reactivos de éster NHS y maleimida en los extremos opuestos de un brazo espaciador aromático de longitud media (11,6 angstroms).

Características de SMPB:

• Grupos reactivos: Éster NHS y maleimida
• Reactivo a: grupos amino y sulfhidrilo
• Cadena extendida análoga de MBS
• No escindible
• Insolubles en agua (disolver primero en DMF o DMSO)
• Los conjugados formados con SMPB son más estables en suero que los SPDP

Referencias del producto:
Guía de aplicación entrecruzada: búsqueda de referencias literarias recientes para este producto

Productos relacionados
Sulfo-SMPB (sulfosuccinimidil 4-(N-maleimidofenilo)butirato)
Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.
Especificaciones
Permeabilidad celularSí
DescripciónSMPB
FormularioPolvo
Método de etiquetadoEtiqueta química
Peso molecular356.33
PegiladoNo
Línea de productosPierce
Cantidad50 mg
Fracción reactivaMaleimida, Éster NHS
Condiciones de envíoAmbiente
SolubilidadDMF, DMSO
Longitud del brazo del separador11,6 Å
Soluble en aguaNo
Reactividad químicaAmino-sulfhidrilo
CleavableNo
Tipo de enlace cruzadoHeterobifuncionales
FormatoEstándar
Tipo de productoEntrecruzador
SeparadorMedio (de 10 a 30 Å)
Unit SizeEach
Contenido y almacenamiento
Tras su recepción, almacenar desecado a 4 °C.

Preguntas frecuentes

Can you provide the shelf-life for SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)?

SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.

Citations & References (4)

Citations & References
Abstract
Covalent attachment of synthetic DNA to self-assembled monolayer films.
Authors:Chrisey LA, Lee GU, O'Ferrall CE
Journal:Nucleic Acids Res
PubMed ID:8760890
'The covalent attachment of thiol-modified DNA oligomers; to self-assembled monolayer silane films on fused silica and oxidized silicon substrates is described. A heterobifunctional crosslinking molecule bearing both thiol- and amino-reactive moieties was used to tether a DNA oligomer (modified at its terminus with a thiol group) to an aminosilane film ... More
Decorin is a novel antagonistic ligand of the Met receptor.
Authors:Goldoni S, Humphries A, Nyström A, Sattar S, Owens RT, McQuillan DJ, Ireton K, Iozzo RV
Journal:J Cell Biol
PubMed ID:19433454
'Decorin, a member of the small leucine-rich proteoglycan gene family, impedes tumor cell growth by down-regulating the epidermal growth factor receptor. Decorin has a complex binding repertoire, thus, we predicted that decorin would modulate the bioactivity of other tyrosine kinase receptors. We discovered that decorin binds directly and with high ... More
Dendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1 diabetes.
Authors:Karumuthil-Melethil S, Perez N, Li R, Prabhakar BS, Holterman MJ, Vasu C
Journal:J Immunol
PubMed ID:20483724
The levels of expression of alternatively spliced variants of CTLA-4 and insufficient CTLA-4 signaling have been implicated in type 1 diabetes. Hence, we hypothesized that increasing CTLA-4-specific ligand strength on autoantigen-presenting dendritic cells (DCs) can enhance ligation of CTLA-4 on T cells and lead to modulation of autoreactive T cell ... More
Visualizing dynamic cytoplasmic forces with a compliance-matched FRET sensor.
Authors:Meng F, Sachs F
Journal:J Cell Sci
PubMed ID:21172803
Mechanical forces are ubiquitous modulators of cell activity but little is known about the mechanical stresses in the cell. Genetically encoded FRET-based force sensors now allow the measurement of local stress in specific host proteins in vivo in real time. For a minimally invasive probe, we designed one with a ... More