The Axiom Canine HD Array was designed as part of the Expert Array Design Program. The array was developed byMás información
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Cantidad:
1 placa
Precio (CLP)
16.412.711
1 plate
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The Axiom Canine HD Array was designed as part of the Expert Array Design Program. The array was developed by screening over 2000 samples using the Axiom Canine Genotyping Array Sets A and B. The samples covered over 50 breeds and were carefully selected with appropriate pedigree to maximize polymorphic content. The array offers over 710,000 markers for validation and discovery of variants associated with specific phenotypes. The content on the array was aligned with the CanFam3 reference genome.
Features include: • Over 710,000 markers with legacy content from in-market arrays including new variants • Functional variants of biological relevance • Intergenic variants based on newly available long non-coding RNA (lnc RNA) data • miRNA variants • Breed-specific markers • Over 150 disease and trait specific markers
Applications • Genome-wide association studies • Veterinary research • Direct-to-consumer applications • A model organism to aid understanding of complex human diseases such as cancer and diabetes
Data from the Axiom Canine HD Array are analyzed using Axiom Analysis Suite and Axiom CNV Summary Tools software. The data can also be exported into long format using the Axiom Long Format Export Tool (AxLE). Automated genotyping analysis with Axiom Analysis Software enables accurate genotyping of samples from various breeds including samples that exhibit in-breeding, a common occurrence in canine species.
What is the starting amount of DNA required for Axiom arrays?
All Axiom arrays (except for Axiom Genome-Wide Pan-African Array Set) require a total of 200 ng DNA. The Axiom Genome-Wide Pan-African Array Set requires a total of 300 ng DNA, or 100 ng DNA per array (there are 3 arrays).
What are the sample requirements for Axiom array processing at the Thermo Fisher Scientific Microarray Research Services Laboratory (MRSL)?
For information regarding our in-house MRSL requirements, please contact us via phone at 888-362-2447 (in North America) or via email at BioinformaticsServices@thermofisher.com.