Search
Citas y referencias (17)
Invitrogen™
BODIPY™ FL C5 (ácido 4,4-difluoro-5,7-dimetil-4-bora-3a,4a-diaza-s-indaceno-3-pentanoico)
El ácido graso verde fluorescente, BODIPY™ FL C5 se puede utilizar como un precursor sintético de una gran variedad deMás información
| Número de catálogo | Cantidad |
|---|---|
| D3834 también denominado D-3834 | 1 mg |
Número de catálogo D3834
también denominado D-3834
Precio (CLP)
-
Cantidad:
1 mg
El ácido graso verde fluorescente, BODIPY™ FL C5 se puede utilizar como un precursor sintético de una gran variedad de fosfolípidos fluorescentes. A diferencia de los fluoróforos como el pireno, la DPH y la NBD, BODIPY™ es relativamente insensible al medio ambiente y es fluorescente tanto en entornos acuosos como lipídicos.
Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.
Especificaciones
Nombre del producto químico o materialÁcidos grasos
Almacenamiento recomendadoAlmacenar en el congelador (de – 5 a – 30 °C) y proteger de la luz.
Forma físicaSolid
Línea de productosBODIPY
Cantidad1 mg
Unit SizeEach
Citations & References (17)
Citations & References
Abstract
Flow cytometry-based binding assay for GPR40 (FFAR1; free fatty acid receptor 1).
Journal:Mol Pharmacol
PubMed ID:18927207
'GPR40 is a G protein-coupled receptor (GPCR) whose endogenous ligands have recently been identified as medium- and long-chain free fatty acids (FFAs), and it is thought to play an important role in insulin release. Despite recent research efforts, much still remains unclear in our understanding of its pharmacology, mainly because
Genetic analysis of digestive physiology using fluorescent phospholipid reporters.
Journal:Science
PubMed ID:11359013
'Zebrafish are a valuable model for mammalian lipid metabolism; larvae process lipids similarly through the intestine and hepatobiliary system and respond to drugs that block cholesterol synthesis in humans. After ingestion of fluorescently quenched phospholipids, endogenous lipase activity and rapid transport of cleavage products results in intense gall bladder fluorescence.
A novel fluorogenic substrate for the measurement of endothelial lipase activity.
Journal:J Lipid Res
PubMed ID:21062953
'Endothelial lipase (EL) is a phospholipase A1 (PLA1) enzyme that hydrolyzes phospholipids at the sn-1 position to produce lysophospholipids and free fatty acids. Measurement of the PLA1 activity of EL is usually accomplished by the use of substrates that are also hydrolyzed by lipases in other subfamilies such as PLA2
Effects of the glucosphingolipid synthesis inhibitor, PDMP, on lysosomes in cultured cells.
Journal:J Lipid Res
PubMed ID:7964184
'The glucosphingolipid synthesis inhibitor, 1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) has a wide range of effects on cell physiology and morphology. Here, we studied the effects of high concentrations of PDMP on cells in culture and found that fluorescent analogs of PDMP targeted to the lysosomes of Chinese hamster ovary (CHO) cells. Overnight incubation
A HPLC-fluorescence detection method for determination of phosphatidic acid phosphohydrolase activity: application in human myocardium.
Journal:Anal Biochem
PubMed ID:18023403
Phosphatidic acid phosphohydrolase (PAP) catalyzes the dephosphorylation of phosphatidic acid (PA) to diacylglycerol, the second messenger responsible for activation of protein kinase C. Despite the crucial role of PAP lipid signaling, there are no data on PAP signaling function in the human heart. Here we present a nonradioactive assay for