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Thermo Scientific Chemicals
Sulfanilamide 98%
Sulfanilamide, CAS # 63-74-1, is an organic sulfur compound that shows antibacterial activities.
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| Catalog Number | Quantity |
|---|---|
| 132855000 | 500 g |
| 132851000 | 100 g |
| 132850025 | 2.5 kg |
Price (EUR)
206,00
Each
Chemical Identifiers
CAS63-74-1
IUPAC Name4-aminobenzene-1-sulfonamide
Molecular FormulaC6H8N2O2S
InChI KeyFDDDEECHVMSUSB-UHFFFAOYSA-N
SMILESNC1=CC=C(C=C1)S(N)(=O)=O
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Specifications
Specification Sheet
Specification SheetAppearance (Form)Crystalline powder
Loss on drying=<0.5 % (1 g, 105°C)
Appearance (Color)White to off-white
Infrared spectrumConforms
HPLC>=97.5 %
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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Sulfanilamide is an organic sulfur compound with antibacterial properties that are structurally similar to the p-aminobenzoic acid (PABA)
- It also has a competitive inhibitory capacity against dihydropteroate synthetases blocking the synthesis of folic acid
- Sulfanilamide competes with PABA for the bacterial enzyme dihydropteroate synthase preventing, the incorporation of PABA into dihydrofolic acid, an immediate precursor of folic acid. This culminates in the inhibition of the bacterial folic acid synthesis and also the de novo synthesis of purines and pyrimidines, resulting in cell growth arrest and cell death.
Applications
- This compound shows antibacterial activity against different species, including gram-positive, gram-negative, and Chlamydia
- In chemical reactions, this compound can act as an intermediate for the preparation of 2,6-disubstituted anilines by electrophilic substitution
- Sulfanilamide shows inhibitory activity against the enzyme, carbonic anhydrase.
RUO – Research Use Only