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Atropine sulfate monohydrate, 97+%

Name: Atropine sulfate monohydrate, 97+%
SKU: 226681000
Price: 290.00 EUR

Atropine sulfate monohydrate, CAS # 5908-99-6, is a muscarinic receptor antagonist. | CAS: 5908-99-6 | H₂SO₄·H₂O | 694.85 g/mol

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Catalog number 226681000

Price (EUR)

290,00

Each

Quantity:

100 g

Packaging:

Glass bottle

Request bulk or custom format

Price (EUR)

290,00

Each

Chemical Identifiers

CAS5908-99-6

IUPAC Name8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate sulfuric acid hydrate

Molecular FormulaC17H27NO8S

InChI KeyPVGPXGKNDGTPTD-UHFFFAOYNA-N

SMILESO.OS(O)(=O)=O.CN1C2CCC1CC(C2)OC(=O)C(CO)C1=CC=CC=C1

Specifications

Specification Sheet

Appearance (Form)Powder or crystals

Specific optical rotation(on anhydrous basis)

Infrared spectrumConforms

Water2.0 to 4.0 % (K.F.)

Specific optical rotation(25°C, 589 nm) (c=10, water) -0.50° to +0.05°

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Atropine is a competitive and reversible antagonist of muscarinic acetylcholine receptors on both central and peripheral neurons
Atropine was originally isolated from the belladonna plant Atropa belladonna but is also found in other Solanaceae plants
Atropine is a drug that can be used to slow heart rate, decrease salivary secretions, and treat poisoning caused by cholinergic or muscarinic agents

Applications

It is used to block activation of muscarinic receptors in laboratory mice
It can be used in a laboratory setting to decrease oral and airway secretions in research animals
Atropine has been used to study heart rate and blood pressure variability in swine

RUO – Research Use Only

General References:

Driessen, A.K.; McGovern, A.E.; Behrens, R.; Moe, A.A.K.; Farrell, M.J.; Mazzone, S.B. A role for neurokinin 1 receptor expressing neurons in the paratrigeminal nucleus in bradykinin-evoked cough in guinea-pigs. J Physiol. 2020, 598(11), 2257-2275.
Egorov, A.V.; Schumacher, D.; Medert, R., Birnbaumer, L.; Freichel, M.; Draguhn, A. TRPC channels are not required for graded persistent activity in entorhinal cortex neurons. Hippocampus. 2019 Nov;29(11):1038-1048. doi: 10.1002/hipo.23094.
Poletto, R.; Janczak, A.M.; Marchant-Forde, R.M.; Marchant-Forde, J.N.; Matthews, D.L.; Dowell, C.A.; Hogan, D.F.; Freeman, L.J.; Lay, D.C. Jr. Identification of low and high frequency ranges for heart rate variability and blood pressure variability analyses using pharmacological autonomic blockade with atropine and propranolol in swine. Physiol Behav. 2011 May 3;103(2):188-96.