Lithocholic acid, 95%
Lithocholic acid, 95%
Lithocholic acid, 95%
Thermo Scientific Chemicals

Lithocholic acid, 95%

Lithocholic acid, CAS # 434-13-9, a bacterial metabolite, is an oligo (ethylene glycol) and a secondary bile acid. | CAS: 434-13-9 | C24H40O3 | 376.581 g/mol
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5 g
25 g
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Catalog number 229090050
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36,65
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Quantity:
5 g
Packaging:
Glass bottle
Request bulk or custom format
Price (EUR)
36,65
Online Exclusive
40,50
Save 3,85 (10%)
Each
Chemical Identifiers
CAS434-13-9
IUPAC Name(4R)-4-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11aR)-7-hydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
Molecular FormulaC24H40O3
InChI KeySMEROWZSTRWXGI-HVATVPOCSA-N
SMILESC[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to light yellow
Appearance (Form)Powder
Infrared spectrumConforms
Melting point182°C to 190°C
HPLC>=94 %
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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Lithocholic acid is a monohydroxy acid, and a secondary bile acid

Applications

  • Lithocholic acid can be used in studies that assess cholestasis
  • It can be used to study hepatic phospholipid regulation and homeostasis of bile acid
RUO – Research Use Only

General References:

  1. Hofmann, A.F. Detoxification of lithocholic acid, a toxic bile acid: relevance to drug hepatotoxicity. Drug Metab Rev. 2004, 36 (3-4), 703-22.
  2. Mikó, E., et al. Lithocholic acid, a bacterial metabolite reduces breast cancer cell proliferation and aggressiveness. Biochim Biophys Acta Bioenerg. 2018, 1859 (9), 958-974.