Bilirubin, 98+%
Element SearchElement SearchStructure SearchStructure Search
Bilirubin, 98+%
Bilirubin, 98+%
Bilirubin, 98+%
Thermo Scientific Chemicals

Bilirubin, 98+%

Bilirubin, CAS # 635-65-4, is a tetrapyrroliccompound found in bile that is a product of heme catabolism. | CAS: 635-65-4 | C33H36N4O6 | 584.67 g/mol
Have Questions?
Change viewbuttonViewtableView
Quantity:
500 mg
1 g
5 g
Packaging:
Glass bottle
ChemDexTry the chem dexTM web app
This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.
Catalog number 230220010
Price (EUR)
179,00
Each
Add to cart
Quantity:
1 g
Packaging:
Glass bottle
Request bulk or custom format
Price (EUR)
179,00
Each
Add to cart
Chemical Identifiers
CAS635-65-4
IUPAC Name3-(2-{[3-(2-carboxyethyl)-5-{[(2Z)-4-ethenyl-3-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene]methyl}-4-methyl-1H-pyrrol-2-yl]methyl}-5-{[(2Z)-3-ethenyl-4-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene]methyl}-4-methyl-1H-pyrrol-3-yl)propanoic acid
Molecular FormulaC33H36N4O6
InChI KeyBPYKTIZUTYGOLE-IFADSCNNSA-N
SMILESCC1=C(C=C)\C(NC1=O)=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(CCC(O)=O)C(C)=C(N2)\C=C2/NC(=O)C(C=C)=C2C)N1
View more
SpecificationsSpecification SheetSpecification Sheet
Appearance (Form)Powder
Water=<1 % (K.F.)
Appearance (Color)Orange to red to brown
Infrared spectrumConforms
UV Lambda max450 to 454 nm (in CHCl3)
View more
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Bilirubin is a degradation product of heme following the activity of heme oxidase. Bilirubin is produced in the reticuloendothelial system and conjugated in the liver. It appears as an orange-yellow pigment that is secreted in the bile
  • High levels of unconjugated bilirubin can result in jaundice, a condition of the yellowing of skin and eyes. This can be toxic and may be a sign of severe liver disease
  • Bilirubin has been seen to have functions including cell signaling, metabolism modulation, and immune regulation
  • It has protective antioxidant activity at moderate levels

Application

  • Bilirubin is widely used in studies of liver function and disease, such as hepatitis or cirrhosis
  • As an antioxidant, bilirubin has been studied in protection against H2O2-mediated cell death
  • It can be used as a scavenger of reactive oxygen species (ROS) or as an inhibitor of NADPH oxidase
RUO – Research Use Only

General References:

  1. Hinds TD Jr, Stec DE. Bilirubin, a Cardiometabolic Signaling Molecule. Hypertension. 2018 Oct;72(4):788-795. doi: 10.1161/HYPERTENSIONAHA.118.11130. Erratum in: Hypertension. 2018 Dec;72(6):e95. PMID: 30354722; PMCID: PMC6205727.
  2. Vítek L, Tiribelli C. Bilirubin: The yellow hormone? J Hepatol. 2021 Dec;75(6):1485-1490. doi: 10.1016/j.jhep.2021.06.010. Epub 2021 Jun 18. PMID: 34153399.