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Taurodeoxycholic acid, sodium salt hydrate, 97%
Taurodeoxycholic acid, sodium salt hydrate, 97%, CAS # 207737-97-1, also known as sodium taurodeoxylate, is a bile acid taurine conjugate of deoxycholic acid, and acts as a detergent. | CAS: 207737-97-1 | C26H44NNaO6S | 521.69 g/mol
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Catalog number 336840010
Price (EUR)
72,80
Each
Quantity:
1 g
Packaging:
Glass bottle
Price (EUR)
72,80
Each
Chemical Identifiers
CAS207737-97-1
IUPAC Namesodium 2-[(4R)-4-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanamido]ethane-1-sulfonate
Molecular FormulaC26H44NNaO6S
InChI KeyYXHRQQJFKOHLAP-FVCKGWAHSA-M
SMILES[Na+].[H][C@@]12CC[C@H]([C@H](C)CCC(=O)NCCS([O-])(=O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C
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Specifications
Specification Sheet
Specification SheetAppearance (Form)Crystalline powder
Heavy metals (as Pb)=<20 ppm
Specific optical rotation+34.5° to +36.5° (20°C, 589 nm) (c=2.5, water)
Solubility(5 % in water) Clear colorless to light yellow
HPLC>=96.0 %
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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Taurodeoxycholic acid, sodium salt hydrate, is a bile acid that is derived from deoxycholic acid
• It is also a conjugate acid of a taurodeoxycholate with detergent activity • It is formed in the liver by conjugating deoxycholate with a taurine group, commonly found in the form of a sodium salt
Applications
• Taurodeoxycholic acid, sodium salt hydrate has been studied to assess the adsorption of bile acids and salts in vegetable fibrous tissue
• It has been used as an anionic detergent important for protein solubilization
• This compound shows cholagogue and choleretic activities
• It has also been used to explore a methodology for determining conjugated and unconjugated bile salts both in serum and jejunal fluids
RUO – Research Use Only
General References:
- Schmid, A.; Neumann, H.; Karrasch, T.; Liebisch, G.; Schäffler, A. Bile acid metabolome after an oral lipid tolerance test by liquid chromatography-tandem mass spectrometry (LC-MS/MS). PLoS One. 2016, 11 (2), e0148869.
- Tangerman, A.; van Schaik, A.; van der Hoek, E.W. Analysis of conjugated and unconjugated bile acids in serum and jejunal fluid of normal subjects. Clin Chim Acta. 1986 Sep 15;159(2):123-32.