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Tyramine hydrochloride, 99%
Tyramine hydrochloride, CAS # 60-19-5, is the hydrochloride salt of tyramine, a biogenic amine derived from the amino acid tyrosine. | CAS: 60-19-5 | C8H12ClNO | 173.64 g/mol
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Catalog number 422381000
Price (EUR)
346,00
Each
Quantity:
100 g
Packaging:
Glass bottle
Price (EUR)
346,00
Each
Chemical Identifiers
CAS60-19-5
IUPAC Namehydrogen 4-(2-aminoethyl)phenol chloride
Molecular FormulaC8H12ClNO
InChI KeyRNISDHSYKZAWOK-UHFFFAOYSA-N
SMILES[H+].[Cl-].NCCC1=CC=C(O)C=C1
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Specifications
Specification Sheet
Specification SheetAppearance (Form)Crystalline powder
Titration Argentometric98.5 to 101.5 % (on dry substance)
Appearance (Color)White to off-white
Infrared spectrumConforms
Solubility(10 % in water) Clear colorless to light yellow
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Tyramine is a naturally occurring monoamine that is derived from the decarboxylation of the amino acid tyrosine utilized in human and invertebrate nervous systems
- Tyramine is synthesized and released from neurons and acts as a neuromodulator upon binding to tyramine receptors
- Tyramine has been found to impact the immune system and cardiovascular system in humans
Applications
- Tyramine may be used to form tyramide conjugate, which can be used as a signal amplification reagent in immunofluorescence assays
- Tyramine-hyaluronic acid conjugates can be used to form biodegradable hydrogels, with utility in drug delivery and tissue engineering
- Tyramine is useful for laboratory studies of neuronal stimulation
RUO – Research Use Only
General References:
- Nagaya, Y.; Kutsukake, M.; Chigusa, S.I.; Komatsu, A. A trace amine, tyramine, functions as a neuromodulator in Drosophila melanogaster. Neurosci Lett. 2002, 329(3), 324-8.
- Lange, A.B. Tyramine: from octopamine precursor to neuroactive chemical in insects. Gen Comp Endocrinol. 2009, 162(1), 18-26.
- Kurisawa, M.; Chung, J.E.; Yang, Y.Y.; Gao, S.J.; Uyama, H. Injectable biodegradable hydrogels composed of hyaluronic acid-tyramine conjugates for drug delivery and tissue engineering. Chem Commun (Camb). 2005, (34), 4312-4.
- Klimovich, B.; Stiewe, T.; Timofeev, O. Inactivation of Mdm2 restores apoptosis proficiency of cooperativity mutant p53 in vivo. Cell Cycle. 2020, 19(1), 109-123.