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Ciprofloxacin, 98%
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Ciprofloxacin, 98%
Ciprofloxacin, 98%
Ciprofloxacin, 98%
Thermo Scientific Chemicals

Ciprofloxacin, 98%

Ciprofloxacin, CAS# 85721-33-1, is a second-generation fluoroquinolone showing antibiotic activity commonly used against susceptible organisms mainly gram-negative bacteria.
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Catalog NumberQuantityPackaging
4496200505gGlass Bottle
44962025025gGlass Bottle
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Catalog number 449620050
Price (EUR)
30,65
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33,60
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Quantity:
5g
Packaging:
Glass Bottle
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Price (EUR)
30,65
Online Exclusive
33,60
Save 2,95 (9%)
Each
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Chemical Identifiers
CAS85721-33-1
IUPAC Name1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Molecular FormulaC17H18FN3O3
InChI KeyMYSWGUAQZAJSOK-UHFFFAOYSA-N
SMILESOC(=O)C1=CN(C2CC2)C2=CC(N3CCNCC3)=C(F)C=C2C1=O
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to light yellow
HPLC>=97.5 %
Sulfated ash=<0.1 %
Appearance (Form)Crystalline powder
Loss on drying=<1 %
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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Ciprofloxacin is considered a synthetic broad-spectrum second-generation compound with antibiotic activity mainly against gram-negative bacteria
• It inhibits bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication, cell division, and causes double-strand breaks in the bacterial chromosome

Applications

• Ciprofloxacin presents more activity against gram-negative bacteria than gram-positive bacteria.
• Ciprofloxacin does not present cross-resistance between fluoroquinolones and other antibiotics classes, which is beneficial in laboratory experiments when other antibiotics are no longer effective

RUO – Research Use Only

Literature References

Nix, D. E.; DeVito, J. M. Ciprofloxacin and norfloxacin, two fluoroquinolone antimicrobials. Clin Pharm. 1987, 6, (2), 105-17.

Sen, et al. Anxiogenic potential of ciprofloxacin and norfloxacin in rats. Singapore Med. J. 2007, 48, (11), 1028-30.