2-Methylcyclohexane-1,3-dione acts as a synthetic intermediate. It is an important starting material, exemplified in a formal synthesis of acorone. It is also used in Organic Synthesis, Pharmaceuticals, Agrochemicals.
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Applications
2-Methylcyclohexane-1,3-dione acts as a synthetic intermediate. It is an important starting material, exemplified in a formal synthesis of acorone. It is also used in Organic Synthesis, Pharmaceuticals, Agrochemicals.
Solubility
Soluble in methanol ( 0.1 g/mL). Insoluble in water.
Notes
Hygroscopic. Store at -20°C. Incompatible with oxidizing agents and moisture.
RUO – Research Use Only
General References:
- Tetsuji Yanami; Michiharu Kato; Masaaki Miyashita; Akira Yoshikoshi, Yasuhiro Itagaki; Kenji Matsuura. Oxygen transfer reaction in acetonylation of 2-methylcyclohexane-1,3-dione with 2-nitropropene. J. Org. Chem. 1977, 42, (16), 2779-2781.
- Useful building block for ring B of the steroid nucleus: J. Am. Chem. Soc., 79, 5542 (1957); J. Chem. Soc., 3441 (1957); Helv. Chim. Acta, 36, 482 (1953). For C-methylation using MeI and Benzyl trimethyl ammonium hydroxide, A14927, see: Org. Synth. Coll., 8, 312 (1993).