Thermo Scientific Chemicals

1,4-Dioxane, 99+%, stab. with ca 5-10ppm BHT, Thermo Scientific Chemicals

Catalog number: A14188.36
500 g, Each
Thermo Scientific Chemicals

1,4-Dioxane, 99+%, stab. with ca 5-10ppm BHT, Thermo Scientific Chemicals

Catalog number: A14188.36
500 g, Each
Quantity
Catalog number: A14188.36
also known as A14188-36
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
123-91-1
IUPAC Name
1,4-dioxane
Molecular Formula
C4H8O2
InChI Key
RYHBNJHYFVUHQT-UHFFFAOYSA-N
SMILES
C1COCCO1
Identification (FTIR)
Conforms
Refractive Index
1.4205-1.4235 @ 20?C
Appearance (Color)
Clear, colorless
Assay (GC)
≥99.0%
Water Content (Karl Fischer Titration)
<0.5%

Description

1,4-Dioxane is used as a stabilizer for 1,1,1-trichloroethane and chlorinated solvents. It acts as a solvent for cellulose acetate, ethyl cellulose, benzyl cellulose, resins, oils, waxes, dyes, other organic and inorganic compounds. It acts as a substitute for tetrahydrofuran due to its higher boiling point and lower toxicity. Further, it is used as an internal standard for proton NMR spectroscopy in deuterium oxide. It plays an important role in liquid scintillation counting in biological procedures, and as a wetting and dispersing agent in textile processing. It is involved in the preparation of dimethylmagnesium by reacting with methylmagnesium bromide, and in the preparation of histological sections for microscopic examination.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1,4-Dioxane is used as a stabilizer for 1,1,1-trichloroethane and chlorinated solvents. It acts as a solvent for cellulose acetate, ethyl cellulose, benzyl cellulose, resins, oils, waxes, dyes, other organic and inorganic compounds. It acts as a substitute for tetrahydrofuran due to its higher boiling point and lower toxicity. Further, it is used as an internal standard for proton NMR spectroscopy in deuterium oxide. It plays an important role in liquid scintillation counting in biological procedures, and as a wetting and dispersing agent in textile processing. It is involved in the preparation of dimethylmagnesium by reacting with methylmagnesium bromide, and in the preparation of histological sections for microscopic examination.

Solubility
Miscible with water, organic solvents, aromatic hydrocarbons and oils.

Notes
Hygroscopic. Incompatible with oxygen, oxidizing agents, halogens, reducing agents, perchlorates and trimethylaluminum.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Flammable liquids
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Carcinogenicity
    Category 1B
    Specific target organ toxicity - (single exposure)
    Category 3
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H319 - Causes serious eye irritation

    H335 - May cause respiratory irritation

    H350 - May cause cancer

    Physical Hazards

    H225 - Highly flammable liquid and vapor

    EU Specific Hazard Statements

    EUH019 - May form explosive peroxides

    EUH066 - Repeated exposure may cause skin dryness or cracking

    Precautionary Statements

    P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower

    P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P312 - Call a POISON CENTER or doctor if you feel unwell

    Additional EU labelling

    Restricted to professional users