Sodium trichloroacetate, 97%
Sodium trichloroacetate, 97%
Sodium trichloroacetate, 97%
Thermo Scientific Chemicals

Sodium trichloroacetate, 97%

CAS: 650-51-1 | C2Cl3NaO2 | 185.36 g/mol
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Catalog number A17004.09
also known as A17004-09
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10 g
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Chemical Identifiers
CAS650-51-1
IUPAC Namesodium trichloroacetate
Molecular FormulaC2Cl3NaO2
InChI KeySAQSTQBVENFSKT-UHFFFAOYSA-M
SMILES[Na+].[O-]C(=O)C(Cl)(Cl)Cl
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to pale cream
Assay (Non-aqueous acid-base Titration)≥96.0 to ≤104.0%
FormCrystals or powder or crystalline powder
Identification (FTIR)Conforms

Sodium trichloroacetate, is used in acid binding reagent in the textile industry in the dying process. Sodium trichloroacetate has been reported previously to be an effective denaturation reagent for proteins was applied to poly(l-lysine) and poly(l-glutamic acid) to see its effects on a coil-to-helix transition and on the chemical reactivities of the ε-amino group of poly(l-lysine). Addition of sodium trichloroacetate to poly-(l-lysine) induced a helical conformation even at neutral pH where the ε-amino group of the polymer was protonated.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sodium trichloroacetate, is used in acid binding reagent in the textile industry in the dying process. Sodium trichloroacetate has been reported previously to be an effective denaturation reagent for proteins was applied to poly(l-lysine) and poly(l-glutamic acid) to see its effects on a coil-to-helix transition and on the chemical reactivities of the ε-amino group of poly(l-lysine). Addition of sodium trichloroacetate to poly-(l-lysine) induced a helical conformation even at neutral pH where the ε-amino group of the polymer was protonated.

Solubility
Soluble in water, ethanol, methanol, acetone.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from strong oxidizing agents. Hygroscopic.
RUO – Research Use Only

General References:

  1. MG Murray. Use of sodium trichloroacetate and mung bean nuclease to increase sensitivity and precision during transcript mapping. Analytical biochemistry. 1986158 (1), 165-170.
  2. AJ Loustalot.; R Ferrer. Studies on the persistence and movement of sodium trichloroacetate in the soil. Agron. J. 19505 (3), 323-325.
  3. Dichlorocarbene precursor by thermolysis: Rec. Trav. Chim., 80, 740 (1961); J. Org. Chem., 29, 1113 (1964), or low temperature reaction using BTEAC in the absence of solvent: Tetrahedron Lett., 91 (1976).
  4. For preparation of phenyl trichloromethyl mercury by addition of dichlorocarbene to phenylmercuric chloride, see: Org. Synth. Coll., 5, 969 (1973).