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Tetrachlorophthalic anhydride, 98%, Thermo Scientific Chemicals
Catalog number: A17404.36
500 g, Each
Thermo Scientific Chemicals
Tetrachlorophthalic anhydride, 98%, Thermo Scientific Chemicals
Catalog number: A17404.36
500 g, Each
Quantity
Catalog number: A17404.36
also known as A17404-36
Price (EUR)
90,90 Online price
101,00
Each
Quantity
-
Chemical Identifiers
CAS
117-08-8
IUPAC Name
tetrachloro-1,3-dihydro-2-benzofuran-1,3-dione
Molecular Formula
C8Cl4O3
InChI Key
AUHHYELHRWCWEZ-UHFFFAOYSA-N
SMILES
ClC1=C2C(=O)OC(=O)C2=C(Cl)C(Cl)=C1Cl
Specifications
Specification SheetAppearance (Color)
White
Form
crystalline powder
Assay (GC)
>97.5%
Assay (Aqueous acid-base Titration)
>97.5%
Description
Protection of amines as their tetrachlorophthalimide derivatives, by reaction with the anhydride in the presence of triethylamine, has been found to be useful in oligosaccharide chemistry. The group is stable to a wide range of reagents but can be selectively cleaved with ethylenediamine at lower temperatures than for the parent phthalimide derivatives; in particular, carboxylic esters are not cleaved under these conditions.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Protection of amines as their tetrachlorophthalimide derivatives, by reaction with the anhydride in the presence of triethylamine, has been found to be useful in oligosaccharide chemistry. The group is stable to a wide range of reagents but can be selectively cleaved with ethylenediamine at lower temperatures than for the parent phthalimide derivatives; in particular, carboxylic esters are not cleaved under these conditions.
Solubility
Hydrolyzes slowly in water.
Notes
Hygroscopic. Store away from oxidizing agents, acids.
Protection of amines as their tetrachlorophthalimide derivatives, by reaction with the anhydride in the presence of triethylamine, has been found to be useful in oligosaccharide chemistry. The group is stable to a wide range of reagents but can be selectively cleaved with ethylenediamine at lower temperatures than for the parent phthalimide derivatives; in particular, carboxylic esters are not cleaved under these conditions.
Solubility
Hydrolyzes slowly in water.
Notes
Hygroscopic. Store away from oxidizing agents, acids.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Serious Eye Damage/Eye Irritation
Category 1
Respiratory Sensitization
Category 1
Skin Sensitization
Category 1
Carcinogenicity
Category 1B
Acute aquatic toxicity
Category 1
Chronic aquatic toxicity
Category 1
Label Elements
Signal Word
Danger
Hazard Statements
H317 - May cause an allergic skin reaction
H318 - Causes serious eye damage
H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled
H350 - May cause cancer
H410 - Very toxic to aquatic life with long lasting effects
Precautionary Statements
P273 - Avoid release to the environment
P202 - Do not handle until all safety precautions have been read and understood
P261 - Avoid breathing dust/fume/gas/mist/vapors/spray
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P308 + P313 - IF exposed or concerned: Get medical advice/attention
Additional EU labelling
Restricted to professional users