4-Bromophenylacetone, 98%
4-Bromophenylacetone, 98%
4-Bromophenylacetone, 98%
Thermo Scientific Chemicals

4-Bromophenylacetone, 98%

CAS: 6186-22-7 | C24H24N2O5S | 452.53 g/mol
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5 g
25 g
Catalog number A19028.06
also known as A19028-06
Price (EUR)
61,70
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Quantity:
5 g
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Price (EUR)
61,70
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Chemical Identifiers
CAS6186-22-7
IUPAC Namemethyl 2-{2-[N-(3,5-dimethylphenyl)benzenesulfonamido]acetamido}benzoate
Molecular FormulaC24H24N2O5S
InChI KeyCDUPPXGKUKTGLU-UHFFFAOYSA-N
SMILESCOC(=O)C1=CC=CC=C1NC(=O)CN(C1=CC(C)=CC(C)=C1)S(=O)(=O)C1=CC=CC=C1
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SpecificationsSpecification SheetSpecification Sheet
FormLiquid
Appearance (Color)Clear pale yellow to yellow
Refractive Index1.5560-1.5600 @ 20?C
Assay (GC)≥97.5%
4-Bromophenylacetone is used to prepare biphenyl-4-yl-acetone by reacting with phenylboronic acid using cesium fluoride as a reagent and palladium phosphine complex as a catalyst.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Bromophenylacetone is used to prepare biphenyl-4-yl-acetone by reacting with phenylboronic acid using cesium fluoride as a reagent and palladium phosphine complex as a catalyst.

Solubility
Miscible with chloroform and dichloromethane. Slightly miscible with water.

Notes
Incompatible with strong oxidizing agents, reducing agents and bases.
RUO – Research Use Only

General References:

  1. Weidmann, V.; Ploog, J.; Kliewer, S.; Schaffrath, M.; Maison, W. Variants of the Prins Cyclization for the Synthesis of Terpenoid Spiroethers and Oxabicyclo[3.3.1]Nonane Derivatives. J. Org. Chem. 2014, 79 (21), 10123-10131.
  2. Sasnouski, G.; Lapanik, V.; Bezborodov, V.; Dabrowski, R.; Dziaduszek, J. Synthesis of fluoro substituted quaterphenyl liquid crystals. Phase Transitions 2014, 87 (8), 783-789.