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Thermo Scientific Chemicals
Trichloroacetyl chloride, 99%
CAS: 76-02-8 | C2Cl4O | 181.821 g/mol
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Catalog number B21675.18
also known as B21675-18
Price (EUR)
59,90
Each
Quantity:
50 g
Price (EUR)
59,90
Each
Chemical Identifiers
CAS76-02-8
IUPAC Nametrichloroacetyl chloride
Molecular FormulaC2Cl4O
InChI KeyPVFOMCVHYWHZJE-UHFFFAOYSA-N
SMILESClC(=O)C(Cl)(Cl)Cl
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Specifications
Specification Sheet
Specification SheetCommentSpecification differs for U.S. and non-U.S. material where indicated
Appearance (Color)Clear colorless to pale yellow or pink
Assay (GC)≥96.0%
Refractive Index1.4685-1.4715 @ 20°C (non-U.S. specification)
Identification (FTIR)Conforms (non-U.S. specification)
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Trichloroacetyl chloride is used in the preparation of dihydro-1H-benzindoles. It is also used in the synthesis of 3-alkylbenzoxazolones It is used in the manufacture of pharmaceuticals and plant protection compounds. It is used for manufacturing the esters and anhydrides of trichloroacetic acid. It is used in the manufacture of pharmaceuticals and organic synthesis intermediate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Trichloroacetyl chloride is used in the preparation of dihydro-1H-benzindoles. It is also used in the synthesis of 3-alkylbenzoxazolones It is used in the manufacture of pharmaceuticals and plant protection compounds. It is used for manufacturing the esters and anhydrides of trichloroacetic acid. It is used in the manufacture of pharmaceuticals and organic synthesis intermediate.
Solubility
Reacts violently with water.
Notes
Moisture sensitive. Store away from oxidizing agents, bases, alcohols, amines and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Trichloroacetyl chloride is used in the preparation of dihydro-1H-benzindoles. It is also used in the synthesis of 3-alkylbenzoxazolones It is used in the manufacture of pharmaceuticals and plant protection compounds. It is used for manufacturing the esters and anhydrides of trichloroacetic acid. It is used in the manufacture of pharmaceuticals and organic synthesis intermediate.
Solubility
Reacts violently with water.
Notes
Moisture sensitive. Store away from oxidizing agents, bases, alcohols, amines and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
General References:
- Ram N Ram and Vineet Kumar Soni. Synthesis of 3-alkylbenzoxazolones from N-alkyl-N-arylhydroxylamines by contiguous O-trichloroacetylation, trichloroacetoxy ortho-shift, and cyclization sequence.J Org Chem.201378(23), 11935-11947.
- Gustavo P Silveira and Joseph P Marino. Enantioselective synthesis of dihydro-1H-benzindoles.J. Org. Chem.201378(7), 3379-3383.